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设备死腔与药物给药

Equipment deadspace and drug administration.

作者信息

Macfie A G

机构信息

Department of Anaesthesia, University of Sheffield.

出版信息

Anaesthesia. 1990 Feb;45(2):145-7. doi: 10.1111/j.1365-2044.1990.tb14283.x.

DOI:10.1111/j.1365-2044.1990.tb14283.x
PMID:2321719
Abstract

Equipment deadspace can be a hazard in drug administration. The aim of this study was to measure the size of this problem. The deadspaces of a selection of cannulae, syringes and epidural catheters were measured by displacing the deadspace volume with water and measuring the weight gain. Between 10 and 30% of a 1-ml intravenous dose will remain in the deadspace depending on the type and gauge of the cannulae. The deadspace of an epidural catheter and filter is approximately 1 ml. All cannulae should be flushed after drug administration. Epidural catheters must be flushed with the same solution as the test dose before insertion.

摘要

设备死腔在药物给药过程中可能构成危害。本研究的目的是测定这一问题的严重程度。通过用水置换死腔容积并测量重量增加来测定一系列套管针、注射器和硬膜外导管的死腔。根据套管针的类型和规格,1毫升静脉注射剂量的10%至30%会残留在死腔内。硬膜外导管和过滤器的死腔约为1毫升。给药后所有套管针均应冲洗。硬膜外导管在插入前必须用与试验剂量相同的溶液冲洗。

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