Smart N G
Department of Anaesthesia and Intensive Care, Flinders Medical Centre, Adelaide, South Australia.
Anaesth Intensive Care. 1991 Aug;19(3):429-33. doi: 10.1177/0310057X9101900322.
This study examined six needle-free injection ports comprising three taps (Sorenson Intralock, Top type L, Viggo Connecta), a one-way valve (Braun RV 1000) and two cannulae with integral injection ports (Vasofix, Venflon 2) with regard to deadspace, protection against blood spillage, and potential difficulties in use. A conventional bung (Baxter), requiring needle use for drug administration, was included for comparison. Where necessary, ports were combined with cannulae in order to simulate clinical practice and allow fair comparison with the Vasofix and Venflon cannulae. Total deadspace was then calculated by filling with normal saline and measuring weight increase. Deadspace (0.10 to 0.43 ml) varied with injection port type and cannula size. Such volumes can contain significant amounts of drug and may be hazardous if not flushed after injection. Only the Vasofix and Venflon Cannulae and the Braun RV1000 protected adequately against blood spillage. Costs varied widely (A$0.19 to A$2.20 excluding cannula). The Vasofix and Venflon 2 cannulae were found to be nearest the ideal.
本研究对六个无针注射端口进行了检测，其中包括三种旋塞（索伦森内部锁定型、顶部L型、维戈连通型）、一个单向阀（贝朗RV 1000）以及两个带有一体式注射端口的套管（瓦索菲克斯、威普隆2），检测内容涉及死腔、防止血液外溢的能力以及使用中可能存在的困难。为作比较，还纳入了一个传统的瓶塞（百特），其给药时需要使用针头。必要时，将端口与套管组合，以模拟临床实践，并便于与瓦索菲克斯和威普隆套管进行公平比较。然后通过注入生理盐水并测量重量增加来计算总死腔。死腔量（0.10至0.43毫升）因注射端口类型和套管尺寸而异。这样的体积可能含有大量药物，如果注射后不冲洗可能会有危险。只有瓦索菲克斯和威普隆套管以及贝朗RV1000能充分防止血液外溢。成本差异很大（不包括套管，从0.19澳元到2.20澳元）。发现瓦索菲克斯和威普隆2套管最接近理想状态。
