Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK.
Cell Stem Cell. 2012 Dec 7;11(6):748-50. doi: 10.1016/j.stem.2012.11.014.
The discovery that phenotypic diversity among differentiated cells results from epigenetic and not genetic differences, and can be reset to restore pluripotency, promises revolutionary advances in medicine. I discuss how this and related seminal discoveries have brought us to an exciting future.
分化细胞表型多样性源自于表观遗传而非遗传差异，且这种差异可以被重置以恢复多能性，这一发现预示着医学的革命性进步。我将讨论这一发现以及相关的开创性发现如何引领我们走向激动人心的未来。
