Litterman Nadia K, Ekins Sean
Collaborative Drug Discovery, 1633 Bayshore Highway, Suite 342, Burlingame, CA 94010, USA.
Collaborative Drug Discovery, 1633 Bayshore Highway, Suite 342, Burlingame, CA 94010, USA; Collaborations in Chemistry, 5616 Hilltop Needmore Road, Fuquay Varina, NC 27526, USA.
Drug Discov Today. 2015 Feb;20(2):247-54. doi: 10.1016/j.drudis.2014.10.006. Epub 2014 Oct 25.
Stem cell research is at an important juncture: despite significant potential for human health and several countries with key initiatives to expedite commercialization, there are gaps in capturing and exploiting the results of past and current research. Here, we propose a concerted plan that could be taken to foster a more collaborative approach and ensure that all research efforts can be leveraged across the community. The creation of a definitive centralized database repository, or at least harmonized data repositories, for stem cell groups in academia and industry, enabling secure selective sharing of data when needed, could provide the core structure that is sought globally and protect intellectual property. The development of minimum information about stem cell experiments (MIASCE) could be key to this development.
尽管对人类健康具有巨大潜力，且有几个国家采取了关键举措来加速商业化，但在获取和利用过去及当前研究成果方面仍存在差距。在此，我们提出一项协同计划，可采取该计划来促进更具协作性的方法，并确保整个科学界能够利用所有研究成果。为学术界和产业界的干细胞研究团队创建一个权威的集中式数据库存储库，或者至少是统一的数据存储库，以便在需要时能够安全地选择性共享数据，这可以提供全球所寻求的核心架构并保护知识产权。制定干细胞实验最小信息规范（MIASCE）可能是这一发展的关键。
