Department of Psychiatry, University of Manitoba, Winnipeg, MB, Canada.
Psychol Med. 2013 Sep;43(9):1941-51. doi: 10.1017/S003329171200284X. Epub 2012 Dec 7.
Controversy exists regarding whether people in the community who meet criteria for a non-psychotic mental disorder diagnosis are necessarily in need of treatment. Some have argued that these individuals require treatment and that policy makers need to develop outreach programs for them, whereas others have argued that the current epidemiologic studies may be diagnosing symptoms of distress that in many cases are self-limiting and likely to remit without treatment. All prior studies that have addressed this issue have been cross-sectional. We examined the longitudinal outcomes of individuals with depressive, anxiety and substance use (DAS) disorder(s) who had not previously received any treatment. Method Data came from a nationally representative US sample. A total of 34 653 non-institutionalized adults (age ≥20 years) were interviewed at two time points, 3 years apart. DAS disorders, mental health service use and quality of life (QoL) were assessed at both time points.
Individuals with a DAS disorder who had not previously received any treatment were significantly more likely than those who had been previously treated to have remission of their index disorder(s) without subsequent treatment, to be free of co-morbid disorder(s) and not to have attempted suicide during the 3-year follow-up period (50.7% v. 33.0% respectively, p < 0.05). At wave 2, multiple linear regression demonstrated that people with a remission of their baseline DAS disorder(s) had levels of functioning similar to those without a DAS disorder.
Individuals with an untreated DAS disorder at baseline have a substantial likelihood of remission without any subsequent intervention.
对于那些符合非精神病性精神障碍诊断标准的社区人群,他们是否一定需要治疗,目前仍存在争议。一些人认为这些人需要治疗,政策制定者需要为他们制定推广计划,而另一些人则认为,目前的流行病学研究可能诊断出的是在许多情况下是自限性的、可能无需治疗就会缓解的痛苦症状。所有之前解决这个问题的研究都是横断面研究。我们研究了从未接受过任何治疗的抑郁、焦虑和物质使用(DAS)障碍患者的纵向结局。
数据来自一项具有全国代表性的美国样本。共有 34653 名非住院成年人(年龄≥20 岁)在两次相隔 3 年的时间点接受了访谈。在两次时间点均评估了 DAS 障碍、精神卫生服务使用情况和生活质量(QoL)。
与之前接受过治疗的患者相比,从未接受过任何治疗的 DAS 障碍患者更有可能在未经后续治疗的情况下,其首发障碍得到缓解,且在 3 年随访期间无共病障碍和自杀未遂(分别为 50.7%和 33.0%,p<0.05)。在第 2 波中,多元线性回归表明,基线 DAS 障碍缓解的人其功能水平与没有 DAS 障碍的人相似。
基线时未接受治疗的 DAS 障碍患者在没有任何后续干预的情况下,有很大的缓解可能性。