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心脏骤停患者胸骨下端体外按压的血流动力学效应

Hemodynamic effect of external chest compressions at the lower end of the sternum in cardiac arrest patients.

作者信息

Cha Kyoung Chul, Kim Ho Jung, Shin Hyung Jin, Kim Hyun, Lee Kang Hyun, Hwang Sung Oh

机构信息

Department of Emergency Medicine, Wonju College of Medicine, Yonsei University, Wonju, Republic of Korea.

出版信息

J Emerg Med. 2013 Mar;44(3):691-7. doi: 10.1016/j.jemermed.2012.09.026. Epub 2012 Dec 4.

Abstract

BACKGROUND

Little is known about the hemodynamic effects of chest compression at different positions on the sternum during cardiopulmonary resuscitation (CPR).

OBJECTIVES

This study aimed to test whether external chest compression at the lower end of the sternum as an alternative position (alternative compression) results in superior hemodynamic effects compared to standard external chest compression (standard compression).

METHODS

We enrolled 17 patients with non-traumatic cardiac arrest who failed to regain spontaneous circulation within 30 min after CPR initiation. Standard compression was begun when cardiac arrest was confirmed. Alternative compression was performed for 2 min if spontaneous circulation was not attained after 30 min of standard CPR. We compared hemodynamics and end-tidal CO2 pressure during the last 2 min of standard compression and during alternative compression.

RESULTS

Peak arterial pressure during compression systole (114 ± 51 vs. 95 ± 42 mm Hg, p < 0.001) and end-tidal CO2 pressure (11.0 ± 6.7 vs. 9.6 ± 6.9 mm Hg, p < 0.05) were higher with alternative than standard compression, whereas arterial pressure during compression diastole, peak right atrial pressure, and coronary perfusion pressure did not differ between standard and alternative compression.

CONCLUSIONS

Compared to standard compression, alternative compression results in a higher peak arterial pressure and end-tidal CO2 pressure, but no change in coronary perfusion pressure.

摘要

背景

关于心肺复苏(CPR)期间在胸骨不同位置进行胸外按压的血流动力学效应,人们了解甚少。

目的

本研究旨在测试在胸骨下端进行胸外按压作为替代位置(替代按压)与标准胸外按压(标准按压)相比是否能产生更好的血流动力学效应。

方法

我们纳入了17例非创伤性心脏骤停患者,这些患者在CPR开始后30分钟内未能恢复自主循环。确认心脏骤停后开始标准按压。如果在标准CPR 30分钟后仍未实现自主循环,则进行2分钟的替代按压。我们比较了标准按压最后2分钟和替代按压期间的血流动力学和呼气末二氧化碳分压。

结果

与标准按压相比,替代按压时收缩期按压峰值动脉压(114±51 vs. 95±42 mmHg,p<0.001)和呼气末二氧化碳分压(11.0±6.7 vs. 9.6±6.9 mmHg,p<0.05)更高,而舒张期按压动脉压、右心房峰值压力和冠状动脉灌注压在标准按压和替代按压之间没有差异。

结论

与标准按压相比,替代按压可导致更高的峰值动脉压和呼气末二氧化碳分压,但冠状动脉灌注压无变化。

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