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[多种慢性病患者药物治疗的适用性]

[Suitability of pharmacological treatment in patients with multiple chronic conditions].

作者信息

Galván-Banqueri Mercedes, Santos-Ramos Bernardo, Vega-Coca María Dolores, Alfaro-Lara Eva Rocío, Nieto-Martín María Dolores, Pérez-Guerrero Concepción

机构信息

Unidad de Gestión Clínica de Farmacia, Hospital Universitario Virgen del Rocío, Sevilla, España.

出版信息

Aten Primaria. 2013 Jan;45(1):6-18. doi: 10.1016/j.aprim.2012.03.011. Epub 2012 Dec 6.

Abstract

OBJECTIVE

To identify tools for measuring the appropriateness of drug therapy useful in patients with multiple chronic conditions.

DESIGN

We performed a literature review.

DATA SOURCES

The following database were consulted (December 2009): Pubmed, EMBASE, CINAHL, PsycINFO and Spanish Medical Index (IME) to detect tools for measuring the appropriateness of treatment in patients with multiple chronic conditions, or otherwise elderly or polypharmacy.

STUDY SELECTION

Studies were identified both qualitative and quantitative methodology, both theoretical and field work, both original and revised work and included work from all areas of the health system. 108 articles were retrieved, of which we selected 59. The consultation of their references include 20 jobs allowed, resulting in a total of 59 articles.

DATA EXTRACTION

Of all the tools identified, the researchers performed a selection of those with possible utility for classified PP. The articles were classified into implicit and explicit methods and the characteristics of the field works were tabulated.

RESULTS

We identified two implicit methods (MAI and Hamdy) and 6 explicit methods (Beers criteria, IPET, STOPP/START, ACOVE, CRIME and NORGEP). None was specific to patients with multiple chronic conditions. The questionnaire MAI, the Beers criteria and its modifications are most often used in literature. The advantages of explicit criteria means that many of them have been developed recently.

CONCLUSION

There are several tools to measure the appropriateness and none of them has been designed for a population of patients with multiple chronic conditions yet, which by its nature requires a specific approach spreads.

摘要

目的

确定可用于患有多种慢性病患者的药物治疗适宜性测量工具。

设计

我们进行了一项文献综述。

数据来源

查阅了以下数据库(2009年12月):PubMed、EMBASE、CINAHL、PsycINFO和西班牙医学索引(IME),以检测用于测量患有多种慢性病、老年患者或使用多种药物患者治疗适宜性的工具。

研究选择

确定了采用定性和定量方法、理论和实地研究、原创和修订作品的研究,包括来自卫生系统所有领域的作品。检索到108篇文章,从中选择了59篇。查阅其参考文献又纳入20篇,最终共有59篇文章。

数据提取

在所有识别出的工具中,研究人员挑选了那些可能对分类的PP有用的工具。文章被分为隐性和显性方法,并将实地研究的特征制成表格。

结果

我们确定了两种隐性方法(MAI和Hamdy)和6种显性方法(Beers标准、IPET、STOPP/START、ACOVE、CRIME和NORGEP)。没有一种方法是针对患有多种慢性病的患者的。问卷MAI、Beers标准及其修改版在文献中使用最为频繁。显性标准的优点是其中许多是最近才开发出来的。

结论

有几种测量适宜性的工具,但尚未有一种是专门为患有多种慢性病的患者群体设计的,而这类患者群体因其性质需要一种特定的方法。

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本文引用的文献

1
Comparison of tools for the assessment of inappropriate prescribing in hospitalized older people.
J Eval Clin Pract. 2012 Dec;18(6):1196-202. doi: 10.1111/j.1365-2753.2011.01758.x. Epub 2011 Aug 24.
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Prevalence of potentially inappropriate prescribing in an acutely ill population of older patients admitted to six European hospitals.
Eur J Clin Pharmacol. 2011 Nov;67(11):1175-88. doi: 10.1007/s00228-011-1061-0. Epub 2011 May 17.
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Clin Pharmacol Ther. 2011 Jun;89(6):845-54. doi: 10.1038/clpt.2011.44. Epub 2011 Apr 20.
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[Presentation of the "National conference on care of patients with chronic diseases"].
Aten Primaria. 2011 Apr;43(4):165-6. doi: 10.1016/j.aprim.2011.02.002.
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Beyond the beers criteria: A comparative overview of explicit criteria.
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Aten Primaria. 2011 Mar;43(3):117-24. doi: 10.1016/j.aprim.2009.12.007. Epub 2010 Mar 21.

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