单纯疱疹 1 型脑炎的绒球小结叶综合征。

The floccular syndrome in herpes simplex type 1 encephalitis.

机构信息

Department of Neurology, Case Western Reserve University, Cleveland, OH, United States.

出版信息

J Neurol Sci. 2013 Feb 15;325(1-2):154-5. doi: 10.1016/j.jns.2012.11.002. Epub 2012 Dec 4.

DOI:10.1016/j.jns.2012.11.002

Abstract

A woman with herpes simplex virus type 1 (HSV1) encephalitis had downbeat nystagmus. The nystagmus was robust in primary gaze but attenuated during upgaze, suggestive of the flocculus involvement. FLAIR and T2-sequences of the brain MRI revealed cerebral lesions typical of HSV1, but also patchy hyperintensities in bilateral flocculi. Cerebrospinal fluid polymerase chain reaction confirmed HSV1 infection. Encephalopathy and downbeat nystagmus gradually improved with acyclovir therapy.

摘要

一位患有单纯疱疹病毒 1 型（HSV1）脑炎的女性出现了向下的眼球震颤。在第一眼位时眼球震颤明显，但在向上注视时减弱，提示绒球受累。脑部 MRI 的 FLAIR 和 T2 序列显示出典型的 HSV1 脑损伤，但也在双侧绒球出现斑片状高信号。脑脊液聚合酶链反应证实 HSV1 感染。在阿昔洛韦治疗后，脑病和向下的眼球震颤逐渐改善。