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系统性红斑狼疮表现为肺炎球菌败血症和化脓性关节炎。

Systemic lupus erythematosus presenting as pneumococcal septicaemia and septic arthritis.

作者信息

Webster J, Williams B D, Smith A P, Hall M, Jessop J D

机构信息

Department of Medicine, University Hospital of Wales, Heath Park, Cardiff.

出版信息

Ann Rheum Dis. 1990 Mar;49(3):181-3. doi: 10.1136/ard.49.3.181.

Abstract

A 50 year old woman presented with pneumococcal septicaemia, septic arthritis, and a lobar pneumonia and was subsequently diagnosed as having systemic lupus erythematosus. The blood film and splenic 99mTc sulphur colloid uptake were normal, although selective functional hyposplenism was shown by the impaired clearance of immunoglobulin coated erythrocytes. Systemic lupus erythematosus presenting with fulminating pneumococcal sepsis in the presence of selective defects in spleen function is previously unreported.

摘要

一名50岁女性因肺炎球菌败血症、化脓性关节炎和大叶性肺炎就诊,随后被诊断为系统性红斑狼疮。尽管免疫球蛋白包被红细胞清除功能受损显示有选择性功能性脾功能减退,但血涂片和脾脏99mTc硫胶体摄取正常。以前未见有报道系统性红斑狼疮在存在脾脏功能选择性缺陷的情况下出现暴发性肺炎球菌败血症。

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本文引用的文献

5
Splenic atrophy in systemic lupus erythematosus.系统性红斑狼疮中的脾萎缩
Ann Intern Med. 1982 Jan;96(1):40-3. doi: 10.7326/0003-4819-96-1-40.
6
Hyposplenism in systemic lupus erythematosus.系统性红斑狼疮中的脾功能减退
Br J Rheumatol. 1983 Aug;22(3):176-8. doi: 10.1093/rheumatology/22.3.176.
8
The role of complement in host resistance to bacteria.补体在宿主抗细菌感染中的作用。
Springer Semin Immunopathol. 1983;6(4):349-60. doi: 10.1007/BF02116279.
9
Hazard of overwhelming infection after splenectomy in childhood.儿童脾切除术后暴发性感染的风险
N Engl J Med. 1967 Jun 1;276(22):1225-9. doi: 10.1056/NEJM196706012762203.

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