Department of Interventional Radiology, The Heart of England NHS Foundation Teaching Hospital, Heartlands Hospital, Birmingham B5 5SS, UK.
Postgrad Med J. 2013 Mar;89(1049):157-64. doi: 10.1136/postgradmedj-2012-131212. Epub 2012 Dec 8.
Deep venous thrombosis is a common life-threatening disorder with a significant mortality rate. The current standard anticoagulation therapy has proven inadequate in prevention of long-term post-thrombotic symptoms in patients with large clot burdens. Over the last two decades, advances in endovascular therapies have delivered a range of new treatment options including catheter-directed thrombolysis, percutaneous mechanical thrombectomy, venoplasty and stenting and inferior vena caval filter devices. Although there has been growing experience and guidelines in the treatment of deep vein thrombosis, there remains a wide variation in clinical practice nationally. This paper aims to raise the awareness of these emerging therapies and reviews the available evidence for their use.
深静脉血栓形成是一种常见的危及生命的疾病，死亡率很高。目前的标准抗凝治疗已被证明在预防大栓子负荷患者的长期血栓后症状方面效果不足。在过去的二十年中，血管内治疗技术的进步提供了一系列新的治疗选择，包括导管定向溶栓、经皮机械血栓切除术、血管成形术和支架置入以及下腔静脉滤器装置。尽管在深静脉血栓形成的治疗方面已经积累了越来越多的经验和指南，但在全国范围内，临床实践仍然存在很大差异。本文旨在提高对这些新兴治疗方法的认识，并回顾其应用的现有证据。
