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锁骨胸骨端的磁共振成像在法医年龄推断中的应用:走向更可靠的年龄推断。

Magnetic resonance imaging of the sternal extremity of the clavicle in forensic age estimation: towards more sound age estimates.

机构信息

Department of Radiology, Ghent University, Ghent, Belgium.

出版信息

Int J Legal Med. 2013 May;127(3):677-89. doi: 10.1007/s00414-012-0798-z. Epub 2012 Dec 9.

Abstract

OBJECTIVES

The development of the sternal extremity of the clavicle was examined prospectively with magnetic resonance imaging (MRI) for forensic bone age assessment. The objectives were to examine whether these results were comparable with the literature on plain radiography and CT, to provide age prediction intervals that correctly reflect the high variability in clavicular growth among individuals and to investigate whether MRI of the clavicle can be used to differentiate between individuals younger or older than 18 years.

METHODS

The clavicles of 220 volunteers (16-26 years) were examined with 3-T MRI and evaluated according to the Schmeling and Kreitner classification (Schmeling, Int J Legal Med 118:5-8, 2004; Kreitner, Eur Radiol 8:1116-1122, 1998). An additional hand/wrist radiograph was taken and evaluated according to Greulich and Pyle (1959). After a descriptive analysis, a multivariate ordinal regression model was fitted and embedded in a Bayesian framework based on Thevissen et al. (Int J Legal Med 124:35-42, 2009).

RESULTS

The descriptive results were concordant with the literature, although the Kreitner classification is recommended and simultaneous evaluation of the hand is considered a basic requirement (Schmeling, Int J Legal Med 118:5-8, 2004). The 95 % credibility interval for both genders with bilateral stage IV is 20-26 years. The corresponding estimated probability of being younger than 18 years is 0.8 % in females and 0.2 % in males.

CONCLUSION

MRI of the sternal extremity of the clavicle can be used to differentiate between being younger or older than 18, but a simultaneous evaluation of the hand/wrist is essential. Future evaluation of the predictive performance of the model, using comparable but larger reference samples, is necessary to validate these results.

摘要

目的

通过前瞻性磁共振成像(MRI)检查锁骨胸骨端,进行法医骨龄评估。目的是检验这些结果是否与普通 X 射线和 CT 的文献一致,提供能正确反映个体锁骨生长高度变异性的年龄预测区间,并探讨 MRI 能否用于区分 18 岁以下和 18 岁以上的个体。

方法

对 220 名志愿者(16-26 岁)的锁骨进行 3T MRI 检查,并根据 Schmeling 和 Kreitner 分类(Schmeling,Int J Legal Med 118:5-8, 2004;Kreitner,Eur Radiol 8:1116-1122, 1998)进行评估。还拍摄了额外的手/腕部 X 光片,并根据 Greulich 和 Pyle(1959)进行评估。在描述性分析后,拟合了一个多变量有序回归模型,并基于 Thevissen 等人的研究(Int J Legal Med 124:35-42, 2009)嵌入贝叶斯框架。

结果

描述性结果与文献一致,尽管 Kreitner 分类是推荐的,同时评估手部被认为是基本要求(Schmeling,Int J Legal Med 118:5-8, 2004)。双侧 IV 期的男女 95%可信度区间为 20-26 岁。女性小于 18 岁的估计概率为 0.8%,男性为 0.2%。

结论

锁骨胸骨端的 MRI 可用于区分 18 岁以下或以上的个体,但同时评估手/腕是必不可少的。需要使用可比但更大的参考样本,对模型的预测性能进行未来评估,以验证这些结果。

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