Department of Work Physiology and Ergonomics, Nofer Institute of Occupational Medicine, Łódź, Poland.
Int J Occup Med Environ Health. 2012 Sep;25(4):446-55. doi: 10.2478/s13382-012-0059-x. Epub 2012 Dec 6.
The aim of the study was to assess the mechanism of cardiovascular impairments in workers exposed to UHF-VHF radio frequency electromagnetic fields (EMF).
Heart rate variability (HRV) was analysed using 512 normal heart beats registered at rest. The analysis concerned time-domain (STD R-R) and frequency-domain (VLF, LF, HF) parameters of HRV. Fifty nine workers (group I) with low-level and 12 workers (group II) with high-level exposure were examined. The mean age of the subjects was 47 ± 9 years and 41 ± 14 years, and mean exposure duration 19.1 ± 8.8 years and 13 ± 4 years, in groups I and II, respectively. The groups were divided according to: E(max), E(dose), E(mean) for frequencies UHF, VHF and UHF+VHF: The control group consisted of 42 non-exposed subjects, aged 49 ± 8 years. Statistical analysis comprised one-way analysis of variance, covariance analysis and logistic regression models.
In the exposed groups, the heart rate was higher than in the control one. Standard deviation of R-R intervals (STD R-R) was found to be significantly (p = 0.0285) lower in group I (42.5 ± 24.7 ms) compared to the control group (62.9 ± 53.5 ms). The risk of lowered STD R-R was significantly increased (OR = 2.37, p = 0.023) in group II. Both exposed groups presented significantly higher VLF and LF values than the control group (p = 0.005 and p = 0.0025, respectively). The EMF-exposed groups were characterised by the dominance of the sympathetic system (LF/HF 1.3 ± 0.35).
The results indicate that exposure to radiofrequency EMF may affect the neurovegetative regulation.
本研究旨在评估接触超高频-甚高频射频电磁场（EMF）的工人心血管损伤的机制。
使用在休息时记录的 512 个正常心跳对心率变异性（HRV）进行分析。分析涉及时域（STD R-R）和频域（VLF、LF、HF）HRV 参数。对 59 名低水平暴露的工人（I 组）和 12 名高水平暴露的工人（II 组）进行了检查。受试者的平均年龄分别为 I 组 47±9 岁和 II 组 41±14 岁，平均暴露时间分别为 I 组 19.1±8.8 年和 II 组 13±4 年。I 组和 II 组分别根据 E(max)、E(dose)、E(mean)（UHF、VHF 和 UHF+VHF 的频率）进行分组：对照组由 42 名未接触的受试者组成，年龄为 49±8 岁。统计分析包括单向方差分析、协方差分析和逻辑回归模型。
暴露组的心率高于对照组。I 组（42.5±24.7ms）的 R-R 间期标准差（STD R-R）明显低于对照组（62.9±53.5ms）（p=0.0285）。II 组 STD R-R 降低的风险显著增加（OR=2.37，p=0.023）。两个暴露组的 VLF 和 LF 值均明显高于对照组（p=0.005 和 p=0.0025）。暴露于 EMF 的组表现出交感神经系统占主导地位（LF/HF 1.3±0.35）。
结果表明，接触射频 EMF 可能会影响神经植物性调节。
