Fleming Paul F, Richards Susie, Waterman Kelly, Davis Peter G, Kamlin C Omar F, Stewart Michael, Sokol Jenni
Newborn Emergency Transport Service (NETS) Victoria, Melbourne, Victoria, Australia.
J Paediatr Child Health. 2013 Mar;49(3):E227-31. doi: 10.1111/jpc.12025. Epub 2012 Dec 11.
Viral bronchiolitis is the most common lower respiratory tract infection in children less than 12 months of age. Prematurity is an independent risk factor for disease severity. Many infected infants require hospitalisation and those living in regional centres frequently require transfer to metropolitan hospitals capable of providing assisted ventilation.
We reviewed infants with bronchiolitis transported by the Victorian Newborn Emergency Transport Service between January 2003 and June 2007. We compared the clinical presentation and treatment required by infants born preterm with those of their term counterparts.
Of the 192 infants transported, 92 were born preterm. Preterm infants were younger at time of transport (mean post-menstrual age 41 weeks vs. 45 weeks) and were more likely to require invasive ventilation (60% vs. 32%, P < 0.001) and to receive a fluid bolus (47% vs. 34%, P = 0.04) when compared with infants who had been born at term. Apnoea, either as a presenting symptom or in combination with respiratory distress, was more common in the preterm group (70% vs. 36%, P < 0.001).
Higher illness severity should be anticipated in ex-preterm infants who present with bronchiolitis. Preterm infants with bronchiolitis are more likely to require invasive ventilation and fluid resuscitation than term infants, suggesting the need for a lower threshold for referral and medical retrieval.
病毒性细支气管炎是12个月以下儿童最常见的下呼吸道感染。早产是疾病严重程度的独立危险因素。许多受感染的婴儿需要住院治疗,而那些生活在地区中心的婴儿经常需要转送到能够提供辅助通气的大城市医院。
我们回顾了2003年1月至2007年6月间由维多利亚州新生儿紧急转运服务转运的细支气管炎婴儿。我们比较了早产婴儿与其足月儿的临床表现和所需治疗。
在192名转运的婴儿中,92名是早产儿。与足月儿相比,早产儿转运时年龄更小(平均孕龄41周对45周),更有可能需要有创通气(60%对32%,P<0.001)和接受液体冲击治疗(47%对34%,P=0.04)。呼吸暂停,无论是作为首发症状还是与呼吸窘迫合并出现,在早产组中更常见(70%对36%,P<0.001)。
对于出现细支气管炎的早产出院婴儿,应预期其疾病严重程度更高。与足月儿相比,患细支气管炎的早产儿更有可能需要有创通气和液体复苏,这表明需要降低转诊和医疗转运的阈值。