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围手术期非产科硬膜外穿刺后即刻并发症的发生率及预测因素。

Incidence and predictors of immediate complications following perioperative non-obstetric epidural punctures.

机构信息

Department of Anaesthesiology, University Hospital of Munich, Marchioninistr, 15, 81377, Munich, Germany.

出版信息

BMC Anesthesiol. 2012 Dec 10;12:31. doi: 10.1186/1471-2253-12-31.

Abstract

BACKGROUND

Epidural Anesthesia (EA) is a well-established procedure. The aim of the present study was to evaluate the incidence of immediate complications following epidural puncture, such as sanguineous puncture, accidental dural perforation, unsuccessful catheter placement or insufficient analgesia and to identify patient and maneuver related risk factors.

METHODS

A total of 7958 non-obstetrical EA were analyzed. The risk of each complication was calculated according to the preconditions and the level of puncture. For probabilistic evaluation we used a logistic regression model with forward selection.

RESULTS

The risk of sanguineous puncture (n = 247, 3.1%) increases with both the patient's age (P = 0.013) and the more caudal the approach (P < 0.01). Dural perforation (n = 123, 1.6%) was found to be influenced only by advanced age (P = 0.019). Unsuccessful catheter placement (n = 68, 0.94%) occurred more often in smaller individuals (P < 0.001) and at lower lumbar sites (P < 0.01). Amongst all cases with successful catheter placement a (partial) insufficient analgesia was found in 692 cases (8.8%). This risk of insufficient analgesia decreased with patient's age (P <0 .01), being least likely for punctures of the lower thoracic spine (P < 0.001).

CONCLUSIONS

Compared to more cranial levels, EA of the lower spine is associated with an increased risk of sanguineous and unsuccessful puncture. Insufficient analgesia more often accompanies high thoracic and low lumbar approaches. The risk of a sanguineous puncture increases in elderly patients. Gender, weight and body mass index seem to have no influence on the investigated complications.

摘要

背景

硬膜外麻醉(EA)是一种成熟的程序。本研究的目的是评估硬膜外穿刺后即刻并发症的发生率,如血性穿刺、意外硬膜穿孔、导管放置失败或镇痛不足,并确定与患者和操作相关的危险因素。

方法

共分析了 7958 例非产科 EA。根据穿刺前的条件和穿刺水平计算每种并发症的风险。对于概率评估,我们使用带有向前选择的逻辑回归模型。

结果

血性穿刺的风险(n=247,3.1%)随着患者年龄的增加(P=0.013)和穿刺部位越靠尾骨而增加(P<0.01)。硬膜穿孔(n=123,1.6%)仅受年龄增加的影响(P=0.019)。导管放置失败(n=68,0.94%)在较小的个体中更常见(P<0.001),在较低的腰椎部位更常见(P<0.01)。在所有成功放置导管的病例中,有 692 例(8.8%)存在(部分)镇痛不足。这种镇痛不足的风险随着患者年龄的增加而降低(P<0.01),在较低的胸椎穿刺时最低(P<0.001)。

结论

与颅部水平相比,下脊柱的 EA 与血性和导管放置失败的风险增加相关。不足的镇痛更常伴随高胸段和低腰段的穿刺。老年患者的血性穿刺风险增加。性别、体重和体重指数似乎对所研究的并发症没有影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9e4/3566923/5259d064979b/1471-2253-12-31-1.jpg

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