Verstraete S, Walters M A, Devroe S, Roofthooft E, Van de Velde M
Department of Anesthesiology, University Hospitals Gasthuisberg, Leuven, Belgium.
Acta Anaesthesiol Scand. 2014 Nov;58(10):1233-9. doi: 10.1111/aas.12394.
Accidental dural puncture (ADP) and post-dural puncture headache (PDPH) are important complications of obstetric regional anesthesia. Inserting the catheter intrathecally after ADP to prevent PDPH has gained popularity. Nonetheless, data on the effect of an intrathecal catheter on PDPH and epidural blood patch (EBP) rates are mixed. Our primary objective was to examine if spinal catheterization reduces the incidence of PDPH after ADP in obstetric patients.
Anesthetic records of 29,749 regional blocks performed between January 1997 and July 2013 were analyzed retrospectively. In all blocks containing an epidural component, 18-gauge epidural needles were used. All patients who experienced a witnessed ADP or PDPH without ADP were identified. Data from patients with or without a prolonged spinal catheter were compared.
There were 128 events of witnessed ADP (0.43%). Following known ADP, 39 women had an epidural catheter placed at a different level and 89 had an intrathecal catheter (20-gauge) for at least 24 h. Sixty-one patients developed PDPH after observed ADP (48%). Prolonged intrathecal catheter placement significantly reduced the incidence of PDPH after ADP to 42% compared with 62% in those who have the catheter re-sited epidurally [odds ratio = 2.3 (95% confidence interval 1.04-4.86); P = 0.04].
The incidence of ADP, PDPH and blood patching is similar with previously published studies. After witnessed ADP, inserting the epidural catheter intrathecally significantly reduced the incidence of PDPH.
意外硬膜穿破(ADP)和硬膜穿破后头痛(PDPH)是产科区域麻醉的重要并发症。ADP后鞘内插入导管以预防PDPH已逐渐流行。尽管如此,关于鞘内导管对PDPH和硬膜外血贴(EBP)发生率影响的数据并不一致。我们的主要目的是研究在产科患者中,脊髓置管是否能降低ADP后PDPH的发生率。
回顾性分析1997年1月至2013年7月间进行的29749例区域阻滞麻醉记录。在所有包含硬膜外成分的阻滞中,均使用18号硬膜外穿刺针。识别出所有发生明确ADP或无ADP的PDPH患者。比较有无留置延长脊髓导管患者的数据。
发生128例明确的ADP事件(0.43%)。在已知发生ADP后,39名女性在不同节段放置了硬膜外导管,89名女性留置了20号鞘内导管至少24小时。61例患者在观察到ADP后发生了PDPH(48%)。与硬膜外重新置管的患者相比,延长鞘内导管留置时间显著降低了ADP后PDPH的发生率,降至42%,而硬膜外重新置管患者的发生率为62%[优势比=2.3(95%置信区间1.04 - 4.86);P = 0.04]。
ADP、PDPH和血贴的发生率与先前发表的研究相似。在明确发生ADP后,鞘内插入硬膜外导管显著降低了PDPH的发生率。