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腹腔镜活体供肾切除术:单中心比较手辅助与标准技术的序贯经验。

Laparoscopic living donor nephrectomy: a single-center sequential experience comparing hand-assisted versus standard technique.

作者信息

Kocak Burak, Baker Talia B, Koffron Alan J, Leventhal Joseph R

机构信息

Department of Urology, Ondokuzmayis University School of Medicine, Samsun, Turkey.

出版信息

Urology. 2007 Dec;70(6):1060-3. doi: 10.1016/j.urology.2007.07.018.

Abstract

OBJECTIVES

To analyzed our institution's 8-year experience (October 1997 through March 2006) with laparoscopic donor nephrectomy (LDN) and hand-assisted LDN (HALDN), comparing donor and recipient outcomes.

METHODS

A total of 482 LDNs were compared with 318 HALDNs with respect to donor sex, age, body mass index, hospital length of stay, donor and recipient serum creatinine levels, and incidence and type of complications. All HALDN were performed using hand-assist devices.

RESULTS

Mean (+/-SD) ages were similar in both groups (41 +/- 10 years versus 39 +/- 10 years; P = NS). Mean body mass index was greater in the HALDN compared with the LDN group (29 +/- 5 kg/m2 versus 27 +/- 5 kg/m2; P <0.01). Hospital length of stay was longer in the LDN group (1.6 +/- 0.7 days versus 1.2 +/- 0.6 days; P <0.01). Graft function and donor's 1-week serum creatinine levels were similar (1.9 +/- 1.6 mg/dL versus 1.2 +/- 0.4 mg/dL; P = NS). The intraoperative complication rate for LDN and HALDN was 3.3% and 2.2%, respectively (P = NS). Postoperative complications occurred in 3.3% of LDNs and 4.7% of HALDNs (P = NS). The conversion rate was 1.9% for LDN and 0.6% for HALDN (P <0.01).

CONCLUSIONS

Both LDN and HALDN are safe and effective. Hand-assisted LDN was not associated with an increased risk of incisional morbidity, postoperative ileus, or delayed graft function. The HALDN group experienced as uneventful and as rapid a recovery as the LDN group.

摘要

目的

分析我院1997年10月至2006年3月期间8年的腹腔镜供肾切除术(LDN)和手辅助腹腔镜供肾切除术(HALDN)经验,比较供体和受体的结局。

方法

比较482例LDN和318例HALDN的供体性别、年龄、体重指数、住院时间、供体和受体血清肌酐水平以及并发症的发生率和类型。所有HALDN均使用手辅助装置进行。

结果

两组的平均(±标准差)年龄相似(41±10岁对39±10岁;P=无显著性差异)。与LDN组相比,HALDN组的平均体重指数更高(29±5kg/m²对27±5kg/m²;P<0.01)。LDN组的住院时间更长(1.6±0.7天对1.2±0.6天;P<0.01)。移植肾功能和供体1周时的血清肌酐水平相似(1.9±1.6mg/dL对1.2±0.4mg/dL;P=无显著性差异)。LDN和HALDN的术中并发症发生率分别为3.3%和2.2%(P=无显著性差异)。LDN术后并发症发生率为3.3%,HALDN为4.7%(P=无显著性差异)。LDN的中转率为1.9%,HALDN为0.6%(P<0.01)。

结论

LDN和HALDN均安全有效。手辅助LDN与切口并发症、术后肠梗阻或移植肾功能延迟的风险增加无关。HALDN组的恢复过程与LDN组一样顺利且迅速。

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