Jamil Osama A, Lechpammer Mirna, Prasad Sashank, Litvack Zachary, Dunn Ian F
Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston.
Surg Neurol Int. 2012;3:140. doi: 10.4103/2152-7806.103878. Epub 2012 Nov 27.
Giant cell reparative granulomas (GCRGs) are rare lesions in the cranial bones. We present a case of this rare lesion emanating from the clivus and replacing the sphenoid sinus, a highly unusual location for this entity.
The case and clinical course of a 29-year-old female who presented with a large sphenoid mass are described here. The patient presented with symptoms of severe headache and diplopia; imaging demonstrated a large sphenoid mass which was completely resected via an endoscopic endonasal approach. It was based on the clivus and was shown to be a GCRG.
GCRGs are benign granulomatous lesions which should be considered in the differential in the setting of a sphenoid mass.
巨细胞修复性肉芽肿(GCRGs)是颅骨中罕见的病变。我们报告了一例起源于斜坡并取代蝶窦的这种罕见病变,这一部位对于该病变来说极为罕见。
本文描述了一名29岁女性出现巨大蝶窦肿物的病例及临床过程。患者表现为严重头痛和复视症状;影像学检查显示一个巨大的蝶窦肿物,通过鼻内镜经鼻入路将其完全切除。该肿物起源于斜坡,病理显示为巨细胞修复性肉芽肿。
巨细胞修复性肉芽肿是良性肉芽肿性病变,在蝶窦肿物的鉴别诊断中应予以考虑。