Williams J C, Thorell W E, Treves J S, Fidler M E, Moore G F, Leibrock L G
Skull Base Surg. 2000;10(2):89-93. doi: 10.1055/s-2000-7276.
Giant cell reparative granuloma (GCRG) is an unusual, benign bone lesion that most commonly affects the maxilla and mandible; skull involvement is rare. The etiology is uncertain but may be related to trauma. GCRG is difficult to distinguish from giant cell tumor of the bone and has a lower recurrence rate. Thirteen reports of temporal bone GCRG in 11 patients have been reported. One report of a petrous GCRG in a 3-year-old girl has been identified. A 38-year-old male presented with a 2-year history of fullness in his left ear, ipsilateral hearing loss, and intermittent cacosmia. Computed tomography and magnetic resonance imaging revealed a large left-sided anterior temporal extradural mass. The patient underwent a left frontotemporal craniotomy and resection of a left temporal fossa tumor that involved the petrous and squamous parts of the temporal bone. The patient's post-operative course was uneventful, except for increased hearing loss secondary to opening of the epitympanum. Follow-up at one month revealed no other problems. Histopathology of the specimen was consistent with a giant cell reparative granuloma.
巨细胞修复性肉芽肿(GCRG)是一种罕见的良性骨病变,最常累及上颌骨和下颌骨;累及颅骨者罕见。其病因尚不确定,但可能与创伤有关。GCRG难以与骨巨细胞瘤相鉴别,且复发率较低。目前已有11例患者发生颞骨GCRG的13篇报道。已发现1例3岁女童发生岩部GCRG的报道。一名38岁男性有2年左耳闷胀、同侧听力减退及间歇性恶臭的病史。计算机断层扫描和磁共振成像显示左侧颞叶前部硬膜外有一巨大肿块。患者接受了左额颞开颅手术,切除了累及颞骨岩部和鳞部的左侧颞窝肿瘤。除因上鼓室开放导致听力减退加重外,患者术后恢复顺利。术后1个月随访未发现其他问题。标本的组织病理学检查结果符合巨细胞修复性肉芽肿。