Extragnathic Giant Cell Granuloma as a Rare Consideration for a Periorbital Mass in an Infant: A Case Report.

Giant cell granulomas (GCGs) are a benign condition that commonly affects females in their first and second decades of life and almost exclusively involves the jaws. We describe a rare presentation of a GCG involving the zygomatic bone in a five-month-old infant, an exceedingly uncommon location and age group for this entity. While GCGs are most frequently seen in the mandible or maxilla of young females, to our knowledge, there are no previous reports describing zygomatic involvement in this age group. Through detailed multimodality imaging, surgical pathology, and clinical follow-up, we highlight the diagnostic considerations, recurrence potential, and role of adjuvant therapy in managing this lesion.