McMaster University, Department of Pediatrics, Division of Hematology/Oncology, Rm 3N27, 1280 Main St West, Hamilton, ON, L8S 4K1 Canada.
Hematology Am Soc Hematol Educ Program. 2012;2012:439-43. doi: 10.1182/asheducation-2012.1.439.
The incidence of venous thromboembolism (VTE) in the pediatric population is increasing. Technological advances in medicine and imaging techniques, improved awareness of the disease, and longer survival of life-threatening or chronic medical conditions all contribute to the increase in VTE rates. There is a paucity of data on management of VTE based on properly designed clinical trials, but there is significant advancement in the last 2 decades. This review summarizes the progress made in pediatric thrombosis, including epidemiological changes, advances in anticoagulant agents, and outcomes of VTE.
儿科人群中的静脉血栓栓塞症（VTE）发病率正在上升。医学和影像学技术的进步、对该疾病认识的提高以及危及生命或慢性疾病的生存时间延长，都导致了 VTE 发生率的增加。基于精心设计的临床试验，有关 VTE 管理的数据很少，但在过去 20 年中取得了重大进展。本综述总结了儿科血栓形成方面的进展，包括流行病学变化、抗凝剂的进步以及 VTE 的结局。
Zotero 插件