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基于木通皂苷的中药质量评价对照提取物研究

[Study on reference extracts for quality assessment on traditional Chinese medicines based on akebiae saponin].

作者信息

Yuan Xianda, Gao Huimin, Wang Zhimin, Zhang Qiwei

机构信息

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2012 Aug;37(16):2413-6.

Abstract

On the basis of analysis and summary of current application of reference extracts of traditional Chinese medicine, reference extracts for quality assessment of traditional Chinese medicines are divided into three classes by purpose: 1. herbal or volatile oil reference extracts for TLC identification of original herbal medicines or patent traditional Chinese medicines containing original herbal medicines. 2. component reference extracts for identification of certain components or positioning of chromatographic peaks. 3. reference extracts marked with component content to be determined for quantitative analysis on samples. For the third kind of reference extracts, akebiae saponin was taken as an example for preparation thought and methods in such aspects as preparation process, component identification and content analysis.

摘要

在对中药对照提取物的应用现状进行分析总结的基础上,依据用途将中药质量控制对照提取物分为三类:1. 用于原药材或含原药材的中成药薄层色谱鉴别用的药材对照提取物或挥发油对照提取物;2. 用于某些成分鉴别或色谱峰定位的成分对照提取物;3. 用于样品定量分析的标有含量测定成分的对照提取物。对于第三类对照提取物,以木通皂苷为例,介绍了其在制备工艺、成分鉴别、含量分析等方面的制备思路和方法。

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