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药用植物和中药的味觉感官评价。

The taste sensory evaluation of medicinal plants and Chinese medicines.

作者信息

Kataoka Masumi, Tokuyama Emi, Miyanaga Yohko, Uchida Takahiro

机构信息

School of Pharmaceutical Sciences, Mukogawa Women's University, 11-68 Koshien 9-Bancho, Nishinomiya-shi, Hyogo 663-8179, Japan.

出版信息

Int J Pharm. 2008 Mar 3;351(1-2):36-44. doi: 10.1016/j.ijpharm.2007.09.017. Epub 2007 Sep 21.

Abstract

The purpose of this study was to investigate the use of the artificial taste sensor in the evaluation of 11 medicinal plants and 10 Chinese medicines with bitter and/or astringent tastes, and to assess the possible application of the sensor in the evaluation of taste and quality control of medicinal products. Aqueous extracts of the six bitter medicinal plants could be classified into three types, and those of the five astringent medicinal plants into two types, on the basis of sensor output pattern profiles. These differences seem to derive from the different structures of the main components. In the principal component analysis of the taste sensor output of 10 Chinese medicines, a new measure developed, the 'Euclidean distance', defined as the distance between a control and the targeted substance on the principal component map. This measure offers a possibility for indicating the different tastes of Chinese medicines. Lastly, we confirmed that berberine adsorption on the surface of the artificial membrane of the taste sensor was of the Langmuir type. The berberine content in extracts of medicinal plants could be evaluated by the taste sensor, and it was shown to be possible to use the taste sensor for the quality control of medicinal plants.

摘要

本研究的目的是调查人工味觉传感器在评估11种具有苦味和/或涩味的药用植物及10种中药中的应用,并评估该传感器在药品味道评估和质量控制中的可能应用。基于传感器输出模式图谱,六种苦味药用植物的水提取物可分为三种类型,五种涩味药用植物的水提取物可分为两种类型。这些差异似乎源于主要成分的不同结构。在对10种中药的味觉传感器输出进行主成分分析时,开发了一种新的测量方法,即“欧几里得距离”,定义为主成分图上对照物与目标物质之间的距离。该测量方法为指示中药的不同味道提供了一种可能性。最后,我们证实小檗碱在味觉传感器人工膜表面的吸附属于朗缪尔类型。药用植物提取物中的小檗碱含量可以通过味觉传感器进行评估,结果表明味觉传感器可用于药用植物的质量控制。

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