Skripka E N
Fiziol Zh (1978). 1990 Jan-Feb;36(1):35-42.
An interrelation between the intensity of release of the lysosomal content of circulating neutrophils and the activation degree of granulocytopoiesis and neutrophilia was revealed by means of pharmacological influence on the lysosomal membrane stability in case of hypovolemic hypotension in rabbits. The activation of granulocytopoiesis and neutrophilia increased while intensifying the release of lysosomal factors from the circulating neutrophils and sharply decreased while restricting it. The intensity of hypotension decreased while intensifying the reaction of the lysosomal apparatus of circulating neutrophils and increased while depressing the reaction.
通过对家兔低血容量性低血压时溶酶体膜稳定性施加药理影响，揭示了循环中性粒细胞溶酶体内容物释放强度与粒细胞生成激活程度及中性粒细胞增多之间的相互关系。粒细胞生成激活及中性粒细胞增多在循环中性粒细胞溶酶体因子释放增强时增加，而在其受限时急剧减少。循环中性粒细胞溶酶体装置反应增强时低血压强度降低，而反应受抑制时则增加。
