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[新鲜及冷冻保存骨髓组织凝血因子的研究]

[Study of tissue coagulation factors of native and cryopreserved bone marrow].

作者信息

Lipkan G N, Kogut G I, Mkhitarian L S, Glukhen'kaia G T, Kubrachenko S I

出版信息

Fiziol Zh (1978). 1990 Jan-Feb;36(1):79-81.

PMID:2323448
Abstract

Status of thromboplastin, antiheparin and antithrombin characteristics of the native and cryopreserved bone marrow was studied experimentally on 12 rabbits. It is found that both the native and cryopreserved bone marrow possesses a pronounced and dilution resistant thromboplastin activity, whereas antithrombin and heparin activities were statistically unauthentic. In that connection the bone marrow injected into blood circulation may have different effects depending on the initial state of the recipient blood coagulation. The fact should be taken into account in clinics.

摘要

在12只兔子身上通过实验研究了天然和冷冻保存骨髓的凝血活酶、抗肝素及抗凝血酶特性。结果发现,天然和冷冻保存的骨髓均具有显著且耐稀释的凝血活酶活性,而抗凝血酶和肝素活性在统计学上无显著差异。鉴于此,注入血液循环的骨髓可能因受血者凝血的初始状态不同而产生不同影响。临床中应考虑到这一事实。

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