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在闭锁性角化病和外耳道胆脂瘤中疾病蔓延模式的比较。

A comparison of patterns of disease extension in keratosis obturans and external auditory canal cholesteatoma.

机构信息

Department of Otolaryngology, Jichi Medical University, Saitama Medical Center, Saitama, Japan.

出版信息

Otol Neurotol. 2013 Jan;34(1):91-4. doi: 10.1097/MAO.0b013e318277a5c8.

Abstract

OBJECTIVE

To investigate the different pathways of progression to the middle ear in keratosis obturans (KO) and external auditory canal cholesteatoma (EACC).

STUDY DESIGN

Retrospective case review.

SETTING

Referral hospital otolaryngology department.

PATIENTS

Patients with KO or EACC and middle ear disease who underwent surgical management were included. Four ears of 4 patients (mean age, 41.25 yr) were the KO group, and 5 ears of 4 patients (mean age, 49.5 yr) were the EACC group.

MAIN OUTCOME MEASURES

Intraoperative findings of the middle ear cavity were investigated in KO and EACC groups.

RESULTS

In the KO group, 3 patients had a perforated tympanic membrane and cholesteatoma in the tympanic cavity. The other patient had preoperative right facial palsy. Removal of the keratin plug revealed an adherent tympanic membrane. In intraoperative findings, the tympanic segment of the fallopian canal was found to be eroded because of inflammation. No case initially progressed to the mastoid cavity. Four patients had external auditory canal cholesteatoma with middle ear disease. In EACC group, all patients had initial progression to the mastoid cavity.

CONCLUSION

KO tends to progress initially to the tympanic cavity via a diseased tympanic membrane. EACC tends to progress to the mastoid cavity via destruction of the posterior bony canal. This is the first report to investigate differences in pathway of progression to the middle ear cavity in these 2 diseases.

摘要

目的

研究外耳道胆脂瘤(EACC)和外耳道耵聍栓塞(KO)向中耳进展的不同途径。

研究设计

回顾性病例研究。

设置

转诊医院耳鼻喉科。

患者

纳入患有 KO 或 EACC 并伴有中耳疾病且接受手术治疗的患者。4 名患者的 4 只耳朵(平均年龄,41.25 岁)为 KO 组,4 名患者的 5 只耳朵(平均年龄,49.5 岁)为 EACC 组。

主要观察指标

研究 KO 和 EACC 组中耳腔的术中发现。

结果

在 KO 组中,3 例患者的鼓膜穿孔且鼓室中有胆脂瘤,另 1 例患者术前有右侧面瘫。去除角蛋白栓后发现鼓膜黏连。术中发现,由于炎症,耳咽管鼓部被侵蚀。无 1 例最初向乳突腔进展。4 例患者的外耳道胆脂瘤合并中耳疾病。在 EACC 组中,所有患者均有初始向乳突腔进展。

结论

KO 倾向于通过病变鼓膜最初向鼓室进展,EACC 倾向于通过破坏后骨管向乳突腔进展。这是首次研究这两种疾病向中耳腔进展途径差异的报告。

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