Persaud R A P, Hajioff D, Thevasagayam M S, Wareing M J, Wright A
Department of Otolaryngology, Head and Neck Surgery, Royal National Throat Nose and Ear Hospital London, UK.
Clin Otolaryngol Allied Sci. 2004 Dec;29(6):577-81. doi: 10.1111/j.1365-2273.2004.00898.x.
Keratosis obturans and external ear canal cholesteatomas have been considered as separate entities for the last 20 years, after being regarded as variations of the same disease for at least 87 years. While both disorders are distinct, they do have some overlapping characteristics which may make it difficult to reach a definite diagnosis. This review explores the diagnostic dilemmas which may arise, and discusses the classification, aetiology, pathogenesis and management of these conditions. We concur that external ear canal cholesteatoma and keratosis obturans are different conditions and conclude that the presence of osteonecrosis and focal overlying epithelial loss are the most reliable features favouring the diagnosis of external ear canal cholesteatoma over keratosis obturans. Furthermore, whilst keratosis obturans can be managed successfully by regular aural toilet, external ear canal cholesteatoma may require surgical intervention depending on the extent of the disease.
在被视为同一种疾病的变体至少87年后,角化性外耳道阻塞和外耳道胆脂瘤在过去20年里一直被视为不同的实体。虽然这两种疾病是有区别的,但它们确实有一些重叠的特征,这可能使得难以做出明确的诊断。本综述探讨了可能出现的诊断困境,并讨论了这些病症的分类、病因、发病机制和治疗。我们认同外耳道胆脂瘤和角化性外耳道阻塞是不同的病症,并得出结论,骨坏死和局灶性上皮缺失是支持外耳道胆脂瘤诊断而非角化性外耳道阻塞的最可靠特征。此外,虽然角化性外耳道阻塞可通过定期耳部清理成功治疗,但外耳道胆脂瘤可能需要根据疾病的程度进行手术干预。