Ohshita Naohiro, Tsutsumi Yasuo M, Kasai Asuka, Soga Tomohiro, Kanamura Tomomi, Katayama Toshiko, Iseki Akio, Tomiyama Yoshinobu, Tanaka Katsuya
Department of Anesthesiology, Tokushima University Hospital, Tokushima 770-8503.
Masui. 2012 Nov;61(11):1261-4.
Anaphylaxis during anesthesia is a rare but life-threatening event. Sugammadex is a recently introduced drug that was specifically designed for the reversal of rocuroium and vecuronium-induced neuromuscular block. We describe the cases of a 74-year-old man and a 29-year-old man who developed an anaphylactoid reaction to sugammadex, presenting with cardiovascular collapse. Initial management consisted of fluid administration and intermittent i.v. ephedrine, epinephrine, and hydrocortisone. The patients made uncomplicated recovery and were discharged.
麻醉期间发生过敏反应是一种罕见但危及生命的事件。舒更葡糖钠是一种最近引入的药物，专门设计用于逆转罗库溴铵和维库溴铵引起的神经肌肉阻滞。我们描述了一名74岁男性和一名29岁男性对舒更葡糖钠发生类过敏反应并出现心血管虚脱的病例。初始治疗包括补液以及间歇性静脉注射麻黄碱、肾上腺素和氢化可的松。患者恢复顺利并出院。
