Mitidieri E, Affonso O R
An Acad Bras Cienc. 1979 Dec;51(4):753-6.
Alloxan is an inhibitor of the enzyme xanthine: NAD+ oxido reductase (E.C.1.2.1.37). Alloxan acts as an electron acceptor and competes "in vitro" with the tetrazolium salt used as electron acceptor in the assay system used for the determination of the dehydrogenase activity of the enzyme. The alloxan inhibition was reverted when phenazine methosulfate (PMS) was added to the system.
NAD⁺氧化还原酶(E.C.1.2.1.37)的抑制剂。四氧嘧啶作为电子受体,在用于测定该酶脱氢酶活性的检测系统中,“在体外”与用作电子受体的四唑盐竞争。当向系统中添加硫酸甲酯吩嗪(PMS)时,四氧嘧啶的抑制作用得以逆转。