Mitidieri E, Affonso O R
Acta Biol Med Ger. 1979;38(8):1131-4.
Xanthine dehydrogenase activity was determined in blood serum of rats in which diabetes had been induced by alloxan administration. The results show that there is no statistical significance in the difference found for normal and diabetic rats. Alloxan produced an inhibition in the enzyme activity in animals in which a carbon tetrachloride hepatotoxicity had been induced.
通过给大鼠注射四氧嘧啶诱导糖尿病，测定了这些大鼠血清中的黄嘌呤脱氢酶活性。结果表明，正常大鼠和糖尿病大鼠之间的差异无统计学意义。在已诱导四氯化碳肝毒性的动物中，四氧嘧啶对酶活性产生了抑制作用。
