Amaaki T, Yasumura K, Kami T, Tahara H
Ann Plast Surg. 1979 Nov;3(5):420-4. doi: 10.1097/00000637-197911000-00005.
Seventeen whole-breast tissue specimens of mammary cystic disease were prepared using Marcum's whole-mounting technique. Histological studies were performed on from 10 to 19 slides of tissue containing the suspected pathological foci. Cysts in the cleared breast tissues were numerous, and cyst walls were covered by single-layered duct epithelial cells with some apocrine metaplasia. The most notable findings were frequent minute carcinomatous foci next to the scattering of mammary cysts. The incidence of carcinoma among 17 mammary cystic disease patients was 8, or 47%. Each patient had from one to six minute carcinomatous foci--less than 1 mm in diameter and noninfiltrating. All patients were treated by subcutaneous total mastectomy and immediate breast reconstruction with the Natural-Y mammary prosthesis. In all 17 the results were good. With no hazardous complications. Steps toward immediate breast reconstruction are as imperative psychologically as the total glandectomy is clinically.
采用马克姆全装片技术制备了17例乳腺囊性疾病的全乳组织标本。对含有可疑病理灶的10至19张组织切片进行了组织学研究。清除后的乳腺组织中囊肿众多，囊肿壁被单层导管上皮细胞覆盖，伴有一些大汗腺化生。最显著的发现是在散在的乳腺囊肿旁频繁出现微小癌灶。17例乳腺囊性疾病患者中癌的发生率为8例，即47%。每位患者有1至6个微小癌灶，直径小于1毫米且无浸润。所有患者均接受了皮下全乳切除术，并立即使用Natural-Y乳房假体进行乳房重建。17例患者的结果均良好，无危险并发症。立即进行乳房重建在心理上的必要性与临床全腺切除术一样迫切。
