Chan K H, Reilly J S, Hashida Y
Department of Otolaryngology, University of Pittsburgh School of Medicine, PA.
Int J Pediatr Otorhinolaryngol. 1990 Jan;18(3):227-39. doi: 10.1016/0165-5876(90)90146-i.
Standard laryngotracheal reconstructive procedures are constrained by the availability of grafting materials and the ability to repair large defects. Reconstruction utilizing alloplasts may be ideal, but previous results have generally been poor. We present a two-stage procedure using Proplast to reconstruct large laryngotracheal defects in 6 dogs. A custom-made Proplast implant was inserted into a strap muscle pocket and buccal mucosa was placed in the adjacent peritracheal tissue. The muscle-Proplast composite graft was rotated to repair a large defect (3.25 cm by 2.25 cm). All 6 dogs survived. Endoscopic and histologic studies over 12 months showed continued stabilization and maturation of the implant. We feel that Proplast may be used as an alternative to autograft for reconstructing large laryngotracheal defects when the procedure is staged to allow maximal fibrous ingrowth and the implant is protected from infection.
标准的喉气管重建手术受到移植材料可用性和修复大缺损能力的限制。使用异体植入物进行重建可能是理想的，但以往的结果通常较差。我们介绍一种分两阶段的手术方法，使用普罗普拉斯（Proplast）在6只犬身上重建大的喉气管缺损。将定制的普罗普拉斯植入物插入带状肌袋中，并将颊黏膜置于相邻的气管周围组织中。将肌肉 - 普罗普拉斯复合移植物旋转以修复大的缺损（3.25厘米×2.25厘米）。所有6只犬均存活。12个月的内镜和组织学研究显示植入物持续稳定并成熟。我们认为，当手术分阶段进行以允许最大程度的纤维长入且植入物受到保护免受感染时，普罗普拉斯可作为自体移植的替代物用于重建大的喉气管缺损。
