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萝卜基因组学和遗传学数据库(RadishBase):一个用于萝卜基因组学和遗传学研究的数据库。

RadishBase: a database for genomics and genetics of radish.

机构信息

Key Laboratory of Horticultural Crop Biology and Germplasm Innovation, Ministry of Agriculture, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.

出版信息

Plant Cell Physiol. 2013 Feb;54(2):e3. doi: 10.1093/pcp/pcs176. Epub 2012 Dec 13.

Abstract

Radish is an economically important vegetable crop. During the past several years, large-scale genomics and genetics resources have been accumulated for this species. To store, query, analyze and integrate these radish resources efficiently, we have developed RadishBase (http://bioinfo.bti.cornell.edu/radish), a genomics and genetics database of radish. Currently the database contains radish mitochondrial genome sequences, expressed sequence tag (EST) and unigene sequences and annotations, biochemical pathways, EST-derived single nucleotide polymorphism (SNP) and simple sequence repeat (SSR) markers, and genetic maps. RadishBase is designed to enable users easily to retrieve and visualize biologically important information through a set of efficient query interfaces and analysis tools, including the BLAST search and unigene annotation query interfaces, and tools to classify unigenes functionally, to identify enriched gene ontology (GO) terms and to visualize genetic maps. A database containing radish pathways predicted from unigene sequences is also included in RadishBase. The tools and interfaces in RadishBase allow efficient mining of recently released and continually expanding large-scale radish genomics and genetics data sets, including the radish genome sequences and RNA-seq data sets.

摘要

萝卜是一种重要的经济蔬菜作物。在过去的几年中,该物种积累了大量的基因组学和遗传学资源。为了有效地存储、查询、分析和整合这些萝卜资源,我们开发了萝卜数据库(http://bioinfo.bti.cornell.edu/radish),这是一个萝卜的基因组学和遗传学数据库。目前,该数据库包含萝卜的线粒体基因组序列、表达序列标签(EST)和基因序列及注释、生化途径、EST 衍生的单核苷酸多态性(SNP)和简单重复序列(SSR)标记以及遗传图谱。萝卜数据库旨在通过一系列高效的查询接口和分析工具,使用户能够轻松地检索和可视化重要的生物学信息,这些工具和接口包括 BLAST 搜索和基因序列注释查询接口,以及用于对基因进行功能分类、识别富集的基因本体(GO)术语和可视化遗传图谱的工具。萝卜数据库还包含了一个从基因序列预测的萝卜代谢途径数据库。萝卜数据库中的工具和接口允许对最新发布的和不断扩展的大规模萝卜基因组学和遗传学数据集进行高效挖掘,包括萝卜基因组序列和 RNA-seq 数据集。

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