Kircanski Katharina, Joormann Jutta, Gotlib Ian H
Department of Psychology, Stanford University, Stanford, CA 94305.
Wiley Interdiscip Rev Cogn Sci. 2012;3(3):301-313. doi: 10.1002/wcs.1177. Epub 2012 Mar 28.
Depression is a prevalent and impairing psychiatric disorder that affects how we feel and how we think about ourselves and the world around us. Cognitive theories of depression have long posited that various thought processes are involved in the development, maintenance, and recurrence of depressive episodes. Contemporary research has utilized experimental procedures to examine cognitive processes in depressed individuals as well as the nature of the relation of these processes to the emotion dysregulation that is central to the disorder. For example, investigators have assessed the ways in which depression alters aspects of information processing, including attention and perception, interpretation, and memory processes; this research has generated relatively consistent findings. In addition, researchers have attempted to identify and elucidate the cognitive mechanisms that may link these biases in information processing to emotion dysregulation in depression. These mechanisms include inhibitory processes and deficits in working memory, ruminative responses to negative mood states, and the inability to use positive and rewarding stimuli to regulate negative mood. Results of these investigations converge on the formulation that depression is associated with increased elaboration of negative information, difficulties in cognitive control when processing this information, and difficulties disengaging from this information. Research examining cognitive aspects of depression not only enhances our understanding of this common and costly disorder, but also has implications for the treatment of depression and for future investigations of the biological foundations of this disorder.
抑郁症是一种普遍且具有损害性的精神障碍,它会影响我们的感受以及我们对自己和周围世界的看法。抑郁症的认知理论长期以来一直认为,各种思维过程参与了抑郁发作的发展、维持和复发。当代研究利用实验程序来检验抑郁症患者的认知过程,以及这些过程与该疾病核心的情绪失调之间关系的本质。例如,研究人员评估了抑郁症改变信息处理各个方面的方式,包括注意力和感知、解释以及记忆过程;这项研究得出了相对一致的结果。此外,研究人员试图识别并阐明可能将这些信息处理偏差与抑郁症中的情绪失调联系起来的认知机制。这些机制包括抑制过程和工作记忆缺陷、对负面情绪状态的反复思考反应,以及无法利用积极和有益的刺激来调节负面情绪。这些调查结果集中在这样一种表述上,即抑郁症与负面信息的更多详尽阐述、处理这些信息时的认知控制困难以及难以从这些信息中脱离有关。对抑郁症认知方面的研究不仅增进了我们对这种常见且代价高昂的疾病的理解,而且对抑郁症的治疗以及该疾病生物学基础的未来研究也具有启示意义。