El Ahmed Husein Husein, Cañadas-De la Fuente Guillermo Arturo, Fernández-Castillo Rafael, González-Jiménez Emilio, Cantero-Hinojosa Jesús, Lardón-Fernández Marita
Hospital Universitario San Cecilio, Granada, España.
Biomedica. 2012 Jun;32(2):170-3. doi: 10.1590/S0120-41572012000300002.
Cutaneous candidiasis is a disease that affects children as well as adults. The presentation may be localized or systemic, and with multiple etiological agents. The most prevalent infecting species in children differs from that of the adult.
A case is presented where a congenital cutaneous candidiasis was transmitted to the child during birth.
A full term newborn was exposed to a subclinical vaginal candidiasis infection, and 24 hr after birth, developed congenital cutaneous candidiasis. The etiological agent was Candida albicans, and was associated with sepsis and respiratory distress. Blood cultures, cutaneous biopsy of vesicular lesions, blood tests and lumbar puncture were performed.
Biochemistry and blood count showed a CRP of 5.7 mg/dl, leukocytosis with left shift and mild anemia. After 24 hr, the blood analyses showed an increase in a CRP (7.8 mg/dl) and increased progressively for three days; consequently, a lumbar puncture was performed. Blood culture was positive for Staphylococcus aureus. Cutaneous biopsy confirmed the cutaneous candidiasis.
The early diagnosis is essential to prevent complications derived by the Candida albicans in newborns.
皮肤念珠菌病是一种影响儿童和成人的疾病。其表现可能是局部的或全身性的,且有多种病原体。儿童中最常见的感染菌种与成人不同。
本文介绍了一例先天性皮肤念珠菌病在出生时传染给婴儿的病例。
一名足月儿暴露于亚临床阴道念珠菌感染,出生后24小时患上先天性皮肤念珠菌病。病原体为白色念珠菌,并伴有败血症和呼吸窘迫。进行了血培养、水疱性皮损的皮肤活检、血液检查和腰椎穿刺。
生化检查和血常规显示C反应蛋白为5.7mg/dl,白细胞增多伴左移和轻度贫血。24小时后,血液分析显示C反应蛋白升高(7.8mg/dl),并持续三天逐渐升高;因此,进行了腰椎穿刺。血培养金黄色葡萄球菌呈阳性。皮肤活检确诊为皮肤念珠菌病。
早期诊断对于预防新生儿白色念珠菌引发的并发症至关重要。