• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Characterization of a sulfadiazine-induced lithiasis calculus by physicochemical techniques.应用物理化学技术对磺胺嘧啶诱导结石的特征进行分析。
AAPS PharmSciTech. 2013 Mar;14(1):128-32. doi: 10.1208/s12249-012-9892-2. Epub 2012 Dec 14.
2
Physicochemical characterization of a new respirable form of nedocromil.奈多罗米一种新的可吸入剂型的物理化学特性
J Pharm Sci. 1995 Jun;84(6):692-6. doi: 10.1002/jps.2600840606.
3
[Does carbonate originate from carbonate-calcium crystal component of the human urinary calculus?].[碳酸盐是否源自人类尿路结石的碳酸盐-钙晶体成分？]
Nihon Hinyokika Gakkai Zasshi. 2008 Sep;99(6):681-7. doi: 10.5980/jpnjurol1989.99.681.
4
Quantitative determination of two polymorphic forms of imatinib mesylate in a drug substance and tablet formulation by X-ray powder diffraction, differential scanning calorimetry and attenuated total reflectance Fourier transform infrared spectroscopy.采用X射线粉末衍射、差示扫描量热法和衰减全反射傅里叶变换红外光谱法对原料药和片剂制剂中甲磺酸伊马替尼的两种多晶型进行定量测定。
J Pharm Biomed Anal. 2015 Oct 10;114:330-40. doi: 10.1016/j.jpba.2015.06.011. Epub 2015 Jun 12.
5
Screening of synthetic PDE-5 inhibitors and their analogues as adulterants: analytical techniques and challenges.筛查合成 PDE-5 抑制剂及其类似物作为掺杂物：分析技术和挑战。
J Pharm Biomed Anal. 2014 Jan;87:176-90. doi: 10.1016/j.jpba.2013.04.037. Epub 2013 May 6.
6
Radiographic characteristics of sulfadiazine urolithiasis.
Urology. 2009 Apr;73(4):928.e5-6. doi: 10.1016/j.urology.2008.06.035. Epub 2008 Aug 13.
7
Physical, X-ray diffraction and scanning electron microscopic studies of uroliths.
Indian J Biochem Biophys. 2006 Aug;43(4):226-32.
8
Engineering of a hybrid polymer-lipid nanocarrier for the nasal delivery of tenofovir disoproxil fumarate: physicochemical, molecular, microstructural, and stability evaluation.工程化聚合物-脂质杂化纳米载体用于富马酸替诺福韦二吡呋酯的鼻腔给药：理化性质、分子、微观结构和稳定性评价。
Eur J Pharm Sci. 2015 Apr 25;71:99-111. doi: 10.1016/j.ejps.2015.02.009. Epub 2015 Feb 20.
9
Functional biocompatible magnetite-cellulose nanocomposite fibrous networks: Characterization by fourier transformed infrared spectroscopy, X-ray powder diffraction and field emission scanning electron microscopy analysis.功能性生物相容性磁铁矿-纤维素纳米复合纤维网络：通过傅里叶变换红外光谱、X射线粉末衍射和场发射扫描电子显微镜分析进行表征
Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb 5;136 Pt C:1450-3. doi: 10.1016/j.saa.2014.10.035. Epub 2014 Oct 22.
10
Ultrastructure and mineral composition of urinary calculi from horses.马尿结石的超微结构与矿物质组成
Am J Vet Res. 1994 Oct;55(10):1357-67.

引用本文的文献

1
Combined computational and experimental studies on cysteine-sulfadiazine adduct formation.关于半胱氨酸-磺胺嘧啶加合物形成的计算与实验相结合的研究
Turk J Chem. 2020 Apr 1;44(2):502-517. doi: 10.3906/kim-1908-62. eCollection 2020.

本文引用的文献

1
Solid dispersion as an approach for bioavailability enhancement of poorly water-soluble drug ritonavir.固体分散体作为一种提高难溶性药物利托那韦生物利用度的方法。
AAPS PharmSciTech. 2010 Jun;11(2):518-27. doi: 10.1208/s12249-010-9404-1. Epub 2010 Mar 18.
2
Nanomolar cationic dendrimeric sulfadiazine as potential antitoxoplasmic agent.纳摩尔级阳离子树枝状磺胺嘧啶作为潜在的抗弓形虫药物。
Int J Pharm. 2006 Dec 1;326(1-2):160-8. doi: 10.1016/j.ijpharm.2006.05.068. Epub 2006 Jul 1.
3
[Drug-induced renal calculi].[药物性肾结石]
Ann Urol (Paris). 2006 Apr;40(2):57-68. doi: 10.1016/j.anuro.2006.01.002.
4
Drug-induced renal calculi: epidemiology, prevention and management.药物性肾结石：流行病学、预防与管理
Drugs. 2004;64(3):245-75. doi: 10.2165/00003495-200464030-00003.
5
The etiology of urolithiasis in HIV infected patients.
J Urol. 2003 Feb;169(2):475-7. doi: 10.1097/01.ju.0000046021.43205.d6.
6
Ritonavir: an extraordinary example of conformational polymorphism.利托那韦：构象多态性的一个非凡例子。
Pharm Res. 2001 Jun;18(6):859-66. doi: 10.1023/a:1011052932607.
7
Metabolism and disposition by the rat of 35S-sulfadiazine alone and in the presence of trimethoprim.大鼠对单独的35S-磺胺嘧啶以及在甲氧苄啶存在情况下的代谢与处置。
Drug Metab Dispos. 1979 Mar-Apr;7(2):94-9.

应用物理化学技术对磺胺嘧啶诱导结石的特征进行分析。

Characterization of a sulfadiazine-induced lithiasis calculus by physicochemical techniques.

机构信息

Laboratorio de Análisis Clínicos, Hospital Virgen de la Concha, Zamora, Spain.

出版信息

AAPS PharmSciTech. 2013 Mar;14(1):128-32. doi: 10.1208/s12249-012-9892-2. Epub 2012 Dec 14.

DOI:10.1208/s12249-012-9892-2
PMID:23242555
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3581671/
Abstract

Currently available information on drug lithiasis usually describes the calculi based on the prescriptions given to the patient, but without a physicochemical characterization of the calculi themselves. We here have applied different, complementary, physicochemical techniques for a complete characterization of an unusual urolithiasis calculus. The calculus was characterized using powder X-ray diffraction, infrared spectroscopy, mass spectrometry, 1H-NMR spectroscopy, and scanning electron microscopy. The precise nature of the calculus was identified, being formed by N4-acetylsulfadiazine, so being related to the drugs prescribed to the patient. Analytical techniques widely used in laboratories of Materials Chemistry have proven to be useful tools for characterizing the chemical nature of unusual urolithiasis.

摘要

目前关于药物结石的可用信息通常根据给患者开的处方描述结石，但没有对结石本身进行物理化学特性分析。我们在此应用了不同的、互补的物理化学技术对一种不寻常的尿石症结石进行了全面的特性分析。结石的特性是通过粉末 X 射线衍射、红外光谱、质谱、1H-NMR 光谱和扫描电子显微镜来确定的。结石的精确性质被确定为 N4-乙酰磺胺，因此与给患者开的药物有关。在材料化学实验室中广泛使用的分析技术已被证明是用于表征不寻常尿石症的化学性质的有用工具。