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糖尿病酮症酸中毒的诊断与治疗

Diagnosis and treatment of diabetic ketoacidosis.

作者信息

Wilson Val

机构信息

Centre for Nursing and Healthcare Research, University of Greenwich, London.

出版信息

Emerg Nurse. 2012 Nov;20(7):14-8; quiz 19. doi: 10.7748/en2012.11.20.7.14.c9405.

Abstract

Diabetic ketoacidosis (DKA) is an acute and serious metabolic complication of type 1 diabetes. Caused by severe insulin deficiency leading to hyperglycaemia, DKA is the most common cause of mortality in people with type 1 diabetes under the age of 40. It causes nausea and vomiting, hypothermia, hypotension, cardiac arrhythmia, tachycardia, deep and rapid breathing and, if untreated, can lead to cerebral oedema, coma and death. The survival of patients with DKA can depend, therefore, on the ability of emergency nurses to recognise its signs and symptoms. The most urgent treatment outcomes in emergency settings are the reversal of ketosis and hyperglycaemia, and the prevention of hypokalaemia and hyponatraemia, and these should be followed by hourly biochemical tests to determine treatment alterations. This article describes DKA and how patients with the condition usually present, and outlines its treatment by emergency nurses.

摘要

糖尿病酮症酸中毒(DKA)是1型糖尿病的一种急性严重代谢并发症。由严重胰岛素缺乏导致高血糖引起,DKA是40岁以下1型糖尿病患者最常见的死亡原因。它会引起恶心、呕吐、体温过低、低血压、心律失常、心动过速、呼吸深快,如果不治疗,可导致脑水肿、昏迷和死亡。因此,DKA患者的存活可能取决于急诊护士识别其体征和症状的能力。急诊环境中最紧迫的治疗结果是酮症和高血糖的逆转,以及低钾血症和低钠血症的预防,随后应进行每小时一次的生化检查以确定治疗调整。本文描述了DKA以及患有该病症的患者通常的表现,并概述了急诊护士对其的治疗。

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