正常和白内障晶状体中基因表达的微阵列和表达序列标签的模式。
Patterns of gene expression in microarrays and expressed sequence tags from normal and cataractous lenses.
机构信息
Department of Biology and Center for Tissue Regeneration and Engineering, University of Dayton, Dayton, OH 45469-2320, USA.
出版信息
Hum Genomics. 2012 Sep 1;6(1):14. doi: 10.1186/1479-7364-6-14.
Abstract
In this contribution, we have examined the patterns of gene expression in normal and cataractous lenses as presented in five different papers using microarrays and expressed sequence tags. The purpose was to evaluate unique and common patterns of gene expression during development, aging and cataracts.
摘要
在本研究中，我们使用微阵列和表达序列标签检查了五篇不同文献中正常和白内障晶状体中的基因表达模式。目的是评估在发育、衰老和白内障过程中独特和共同的基因表达模式。
相似文献
1
Patterns of gene expression in microarrays and expressed sequence tags from normal and cataractous lenses.
Hum Genomics. 2012 Sep 1;6(1):14. doi: 10.1186/1479-7364-6-14.
2
Gene expression changes during cataract progression in Sparc null mice: differential regulation of mouse globins in the lens.
Mol Vis. 2004 Jul 20;10:490-511.
3
4
Gene expression profiling of diabetic and galactosaemic cataractous rat lens by microarray analysis.
Diabetologia. 2005 Apr;48(4):790-8. doi: 10.1007/s00125-005-1687-5. Epub 2005 Mar 11.
5
Discrepant expression of microRNAs in transparent and cataractous human lenses.
Invest Ophthalmol Vis Sci. 2012 Jun 22;53(7):3906-12. doi: 10.1167/iovs.11-9178.
6
Genome-wide transcription analysis of histidine-related cataract in Atlantic salmon (Salmo salar L).
Mol Vis. 2009 Jul 9;15:1332-50.
7
Up-regulation of osteonectin/SPARC in age-related cataractous human lens epithelia.
Mol Vis. 1998 Sep 17;4:17.
8
Absence of SPARC leads to impaired lens circulation.
Exp Eye Res. 2009 Sep;89(3):416-25. doi: 10.1016/j.exer.2009.04.008. Epub 2009 May 3.
9
Autophagy and UPR in alpha-crystallin mutant knock-in mouse models of hereditary cataracts.
Biochim Biophys Acta. 2016 Jan;1860(1 Pt B):234-9. doi: 10.1016/j.bbagen.2015.06.001. Epub 2015 Jun 11.
10
Dynamic and differential regulation in the microRNA expression in the developing and mature cataractous rat lens.
J Cell Mol Med. 2013 Sep;17(9):1146-59. doi: 10.1111/jcmm.12094. Epub 2013 Jul 11.
引用本文的文献
1
Transcriptome Meta-Analysis Uncovers Cell-Specific Regulatory Relationships in Embryonic, Juvenile, Adult, and Aged Mouse Lens Epithelium and Fibers.
Invest Ophthalmol Vis Sci. 2025 Apr 1;66(4):42. doi: 10.1167/iovs.66.4.42.
2
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology.
Development. 2024 Jan 1;151(1). doi: 10.1242/dev.202249. Epub 2024 Jan 5.
3
Emerging Trends and Research Foci in Cataract Genes: A Bibliometric and Visualized Study.
Front Genet. 2021 Aug 9;12:610728. doi: 10.3389/fgene.2021.610728. eCollection 2021.
4
RNA sequencing-based transcriptomic profiles of embryonic lens development for cataract gene discovery.
Hum Genet. 2018 Dec;137(11-12):941-954. doi: 10.1007/s00439-018-1958-0. Epub 2018 Nov 11.
5
Systems biology of lens development: A paradigm for disease gene discovery in the eye.
Exp Eye Res. 2017 Mar;156:22-33. doi: 10.1016/j.exer.2016.03.010. Epub 2016 Mar 16.
6
A robust transcriptional program in newts undergoing multiple events of lens regeneration throughout their lifespan.
Elife. 2015 Nov 2;4:e09594. doi: 10.7554/eLife.09594.
7
Ameliorative effects of SkQ1 eye drops on cataractogenesis in senescence-accelerated OXYS rats.
Graefes Arch Clin Exp Ophthalmol. 2015 Feb;253(2):237-48. doi: 10.1007/s00417-014-2806-0. Epub 2014 Sep 30.
本文引用的文献
1
A recurrent mutation in CRYBA1 is associated with an autosomal dominant congenital nuclear cataract disease in a Chinese family.
Mol Vis. 2011;17:1559-63. Epub 2011 Jun 9.
2
3
Genetic epistasis between heparan sulfate and FGF-Ras signaling controls lens development.
Dev Biol. 2011 Jul 1;355(1):12-20. doi: 10.1016/j.ydbio.2011.04.007. Epub 2011 Apr 17.
4
Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning.
Cell. 2011 Apr 29;145(3):383-397. doi: 10.1016/j.cell.2011.03.028.
5
Translational control by the eukaryotic ribosome.
Cell. 2011 Apr 29;145(3):333-4. doi: 10.1016/j.cell.2011.04.006.
6
Novel beta-crystallin gene mutations in Chinese families with nuclear cataracts.
Arch Ophthalmol. 2011 Mar;129(3):337-43. doi: 10.1001/archophthalmol.2011.11.
7
8
Cataract-causing αAG98R-crystallin mutant dissociates into monomers having chaperone activity.
Mol Vis. 2011 Jan 5;17:7-15.
9
The function of FGF signaling in the lens placode.
Dev Biol. 2011 Mar 1;351(1):176-85. doi: 10.1016/j.ydbio.2011.01.001. Epub 2011 Jan 9.
10
Structural and aggregation behavior of the human γD-crystallin mutant E107A, associated with congenital nuclear cataract.
Mol Vis. 2010 Dec 17;16:2822-8.
Zotero 插件