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妊娠期脊髓损伤女性的产科结局。

Obstetric outcomes in women who sustained a spinal cord injury during pregnancy.

机构信息

Department of Spinal Medicine Prince of Wales Hospital, Sydney, New South Wales, Australia.

出版信息

Spinal Cord. 2013 Feb;51(2):170-1. doi: 10.1038/sc.2012.125. Epub 2012 Dec 18.

Abstract

STUDY DESIGN

Case report.

SETTING

Prince of Wales Spinal Cord Injuries Unit, Sydney, Australia.

METHODS

Interrogation of our unit database identified only two women who became spinal cord injured while pregnant; their medical records were reviewed and an unstructured follow-up telephone interview conducted 6 years after discharge. Case 1: CC sustained a fracture dislocation with paraplegia at the sixth thoracic level (T6) in a motorbike accident while she was pregnant, 12-week gestational age (GA). Profound shock and hypoxia complicated the injury and recurrent urinary tract infections complicated the rest of her pregnancy. A baby with arthrogryposis multiplex congenita was delivered at full term. Severe cerebral palsy (CP) and deafness were present at follow-up 6 years later. Case 2: A 33-year-old multigravida, 27 weeks GA, developed sudden, spontaneous onset of paraplegia (T3 ASIA B) due to an extradural haematoma, which was evacuated on the day of admission. Systolic blood pressure was maintained above 90 mm Hg during and after surgery. A normal, healthy boy was delivered by caesarean section at 40 weeks GA and remained so at 6 years.

CONCLUSION

Traumatic spinal cord injury (SCI) with its attendant multiple potential insults to the developing foetus results in a high risk of foetal loss and malformation particularly in the first trimester. However, if the injury occurs later in pregnancy and if blood pressure and oxygenation are maintained, the risk of foetal loss and abnormality may be substantially reduced.

摘要

研究设计

病例报告。

设置

澳大利亚悉尼王子脊髓损伤单位。

方法

查询我们单位的数据库仅发现了两名在怀孕期间发生脊髓损伤的女性;查阅了她们的病历,并在出院后 6 年进行了非结构化的随访电话访谈。病例 1:CC 在怀孕 12 周时,因摩托车事故导致第六胸椎(T6)骨折脱位伴截瘫。严重的休克和缺氧使损伤复杂化,反复的尿路感染使她的妊娠复杂化。足月分娩了一名患有先天性多发性关节挛缩症的婴儿。6 年后随访时存在严重脑瘫(CP)和耳聋。病例 2:一名 33 岁的多产妇,妊娠 27 周,由于硬膜外血肿突然自发出现截瘫(T3 ASIA B),入院当天进行了血肿清除术。手术期间和之后收缩压均维持在 90mmHg 以上。40 周 GA 时通过剖宫产分娩了一名正常、健康的男孩,6 年后仍然如此。

结论

外伤性脊髓损伤(SCI)及其对发育中胎儿的多种潜在损伤会导致胎儿丢失和畸形的高风险,尤其是在孕早期。然而,如果损伤发生在妊娠晚期,并且血压和氧合得到维持,则胎儿丢失和异常的风险可能会大大降低。

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