Arsh Aatik, Darain Haider
KMU Institute of Physical Medicine and Rehabilitation, Khyber Medical University, Peshawar, Pakistan.
Asian Spine J. 2022 Apr;16(2):290-300. doi: 10.31616/asj.2020.0192. Epub 2021 May 6.
Literature regarding pregnant women who sustained traumatic spinal injury during pregnancy is limited. Existing papers are mainly case reports, and this indicates a need for more high-quality research evidence in this area. Therefore, this study was designed to systematically review available literature that reported demographic information, clinical characteristics, and obstetric outcomes of women who sustained spinal injury during pregnancy. Studies published from the earliest record to January 2019, which reported traumatic spinal injury during pregnancy, were included. Studies that have reported pregnancy in patients with pre-existing spinal injury, review articles, commentaries, letter to editors, conference papers, and studies published in languages other than English were excluded. Sixteen studies reporting on 26 women were included. Their mean age was 26.7±5.5 years. Motor vehicle accidents were the main cause of spinal injury (n=15, 58%). Of the cases, four women sustained spinal injury during the 1st trimester of pregnancy, of which one had a spontaneous abortion, one delivered a baby with arthrogryposis multiplex congenital disorder, and the third one delivered a premature baby who died shortly after the delivery. Fifteen women sustained injury during their 2nd trimester, of which 14 delivered normal babies, while six sustained spinal injury during the 3rd trimester. Of these women, five delivered normal babies at term. Outcomes of pregnancy appear significantly affected if a spinal injury occurs during the 1st trimester of pregnancy; however, injuries sustained during the 2nd and 3rd trimesters can have good obstetric outcomes.
关于孕期发生创伤性脊髓损伤的孕妇的文献有限。现有论文主要是病例报告,这表明该领域需要更多高质量的研究证据。因此,本研究旨在系统回顾报告孕期脊髓损伤女性的人口统计学信息、临床特征和产科结局的现有文献。纳入从最早记录到2019年1月发表的报告孕期创伤性脊髓损伤的研究。排除报告既往存在脊髓损伤患者怀孕情况的研究、综述文章、评论、给编辑的信、会议论文以及非英文发表的研究。纳入了16项报告26名女性的研究。她们的平均年龄为26.7±5.5岁。机动车事故是脊髓损伤的主要原因(n=15,58%)。其中,4名女性在妊娠早期发生脊髓损伤,其中1例自然流产,1例分娩出患有先天性多发性关节挛缩症的婴儿,第3例分娩出一名早产婴儿,该婴儿在出生后不久死亡。15名女性在妊娠中期受伤,其中14名分娩出正常婴儿,而6名女性在妊娠晚期发生脊髓损伤。在这些女性中,5名足月分娩出正常婴儿。如果在妊娠早期发生脊髓损伤,妊娠结局似乎会受到显著影响;然而,在妊娠中期和晚期发生的损伤可以有良好的产科结局。