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使用8毫米尖端冷冻消融导管消除房室结折返性心动过速的慢径路:一项18个月的随访研究。

Slow pathway elimination for atrioventricular nodal reentrant tachycardia with the 8-mm tip cryoablation catheter: an 18-month follow-up study.

作者信息

Peyrol Michaël, Sbragia Pascal, Uhry Sabrina, Boccara Gilles, Dolla Eric, Quatre Amandine, Guenoun Maxime, Lévy Samuel, Paganelli Franck

机构信息

Division of Cardiology, Hôpital Nord, Aix-Marseille Université, Marseille, France.

出版信息

J Interv Card Electrophysiol. 2013 Jun;37(1):105-9. doi: 10.1007/s10840-012-9768-0. Epub 2012 Dec 18.

Abstract

PURPOSE

The 9-French 8-mm tip cryoablation catheter confers a high rate of acute slow pathway (SP) elimination and an acceptable short-term outcome in patients with atrioventricular nodal reentrant tachycardia (AVNRT). The aim of this study was to investigate the long-term outcome of patients treated with this electrode in this indication.

METHODS

Eighty-two patients (female = 52) with a mean age of 54.9 ± 17.7 years underwent SP elimination for typical AVNRT with the 8-mm tip cryocatheter in our institution between November 2009 to June 2012. Clinical and procedural characteristics were prospectively collected.

RESULTS

Acute procedural success defined as AVNRT non-inducibility at the end of the procedure was obtained in 81/82 patients (98.7 %). Mean procedure duration and fluoroscopy time were 74.4 ± 28.7 min (range, 35-160 min) and 8.7 ± 5.3 min (range, 2-26 min), respectively. Mean number of energy applications was 4.0 ± 2.4 (range, 2-15). No permanent atrioventricular block was observed. Transient atrioventricular block occurred in 12 patients (14.6 %). Traumatic fast pathway conduction block occurred in one patient before cryoenergy delivery. Using an intention-to-treat analysis, 78 patients (95.1 %) remained free of AVNRT recurrence during a mean follow-up of 17.8 ± 9.3 months.

CONCLUSIONS

This study confirmed that the 8-mm tip cryocatheter is both safe and highly effective for SP conduction elimination in patients with AVNRT and demonstrated a low recurrence rate during a long-term follow-up.

摘要

目的

9 法 8 毫米尖端冷冻消融导管在房室结折返性心动过速(AVNRT)患者中能实现较高的急性慢径路(SP)消除率及可接受的短期预后。本研究旨在探讨在此适应证下使用该电极治疗患者的长期预后。

方法

2009 年 11 月至 2012 年 6 月期间,我院 82 例患者(女性 52 例),平均年龄 54.9±17.7 岁,采用 8 毫米尖端冷冻导管对典型 AVNRT 进行慢径路消除。前瞻性收集临床和手术特征。

结果

81/82 例患者(98.7%)在手术结束时达到急性手术成功,即 AVNRT 不能诱发。平均手术时间和透视时间分别为 74.4±28.7 分钟(范围 35 - 160 分钟)和 8.7±5.3 分钟(范围 2 - 26 分钟)。平均能量应用次数为 4.0±2.4(范围 2 - 15)。未观察到永久性房室传导阻滞。12 例患者(14.6%)出现短暂性房室传导阻滞。1 例患者在冷冻能量释放前发生创伤性快径路传导阻滞。采用意向性分析,78 例患者(95.1%)在平均 17.8±9.3 个月的随访期间未出现 AVNRT 复发。

结论

本研究证实 8 毫米尖端冷冻导管对 AVNRT 患者的慢径路传导消除既安全又高效,且在长期随访中显示出低复发率。

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