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房室结折返性心动过速导管消融术后的长期随访:大量患者中冷冻热能与射频能量的比较

Long-term follow-up after catheter ablation for atrioventricular nodal reentrant tachycardia: a comparison of cryothermal and radiofrequency energy in a large series of patients.

作者信息

Schwagten Bruno, Knops Paul, Janse Petter, Kimman Geert, Van Belle Yves, Szili-Torok Tamas, Jordaens Luc

机构信息

Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.

出版信息

J Interv Card Electrophysiol. 2011 Jan;30(1):55-61. doi: 10.1007/s10840-010-9530-4. Epub 2010 Dec 14.

Abstract

BACKGROUND

Radiofrequency (RF) catheter ablation for atrioventricular nodal reentrant tachycardia (AVNRT) is highly successful but carries a risk for inadvertent atrioventricular block. Cryoablation (cryo) has the potential to assess the safety of a site before the energy is applied.

PURPOSE

The aim of this study was to evaluate the long-term efficacy and safety of cryothermal ablation in a large series of patients and compare it to RF.

METHODS

All consecutive routinely performed AVNRT ablations from our centre between 1999 and 2007 were retrospectively analysed.

RESULTS

In total, 274 patients were elegible: 150 cryoablations and 124 RF. Overall procedural success was 96% (262/274), and equal in both groups, but nine patients were crossed to another arm. Mean fluoroscopy time was longer in the group treated with RF (27 ± 22 min vs. cryo 19 ± 15 min; p = 0.002). Mean procedure time was not different (RF 138 ± 71 min vs. cryo 146 ± 60 min). A permanent pacemaker was necessary in two RF patients. The questionnaire revealed a high incidence of late arrhythmia related symptoms (48%), similar in both groups, with improved perceived quality of life. The number of redo procedures for AVNRT over 4.3 ± 2.5-years follow-up was not statistically different (11% after cryo and 5% after RF).

CONCLUSIONS

Our data confirm that cryo and RF ablation with 4-mm tip catheters for AVNRT are equally effective, even after long-term follow-up.

摘要

背景

房室结折返性心动过速(AVNRT)的射频(RF)导管消融术成功率很高,但存在意外发生房室传导阻滞的风险。冷冻消融术(cryo)有可能在施加能量之前评估某一部位的安全性。

目的

本研究旨在评估大量患者接受冷冻球囊消融术的长期疗效和安全性,并与射频消融术进行比较。

方法

对1999年至2007年期间在我们中心连续常规进行的所有AVNRT消融术进行回顾性分析。

结果

共有274例患者符合条件:150例行冷冻消融术,124例行射频消融术。总体手术成功率为96%(262/274),两组相同,但有9例患者更换为另一种消融方式。接受射频消融术的组平均透视时间更长(27±22分钟 vs. 冷冻消融术组19±15分钟;p = 0.002)。平均手术时间无差异(射频消融术组138±71分钟 vs. 冷冻消融术组146±60分钟)。两名接受射频消融术的患者需要植入永久性起搏器。问卷调查显示,晚期心律失常相关症状的发生率很高(48%),两组相似,患者的生活质量得到改善。在4.3±2.5年的随访中,AVNRT再次消融术的次数无统计学差异(冷冻消融术后为11%,射频消融术后为5%)。

结论

我们的数据证实,使用4毫米尖端导管对AVNRT进行冷冻消融术和射频消融术同样有效,即使经过长期随访也是如此。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/820b/3034882/87f201e27555/10840_2010_9530_Fig1_HTML.jpg

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