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《社区动脉粥样硬化风险研究中的非裔美国人的体力活动与心血管疾病》

Physical activity and cardiovascular disease in African Americans in Atherosclerosis Risk in Communities.

机构信息

Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454, USA.

出版信息

Med Sci Sports Exerc. 2013 May;45(5):901-7. doi: 10.1249/MSS.0b013e31827d87ec.

Abstract

PURPOSE

Although there is substantial evidence that physical activity reduces a person's risk of cardiovascular disease (CVD), few of these studies have included African Americans. The studies that have included African Americans offer inconclusive evidence on the association, and none studied heart failure separately. We used data from the Atherosclerosis Risk in Communities study cohort to examine, in African Americans, the association of physical activity with the incidence of CVD and its major components-stroke, heart failure, and CHD.

METHODS

Participants age 45-64 yr (3707 African Americans and, for comparison, 10,018 Caucasians) had physical activity assessed via questionnaire in 1987 and were followed for incident CVD (n = 1039) through 2008.

RESULTS

After adjustment for potential confounders, physical activity was inversely related to CVD, heart failure, and CHD incidence in both races (P values for trend <0.0001), and with stroke in African Americans. Hazard ratios (95% confidence intervals) for CVD for each higher physical activity category were similar by race: 1.0, 0.65 (0.56-0.75), and 0.59 (0.49-0.71) for African Americans and 1.0, 0.74 (0.66-0.83), and 0.67 (0.59-0.75) for Caucasians (P value for interaction = 0.38).

CONCLUSIONS

Our findings reinforce recommendations that regular physical activity is important for CVD risk reduction in African Americans as well as Caucasians and support the idea that some physical activity is better than none.

摘要

目的

尽管有大量证据表明身体活动可降低个体患心血管疾病(CVD)的风险,但这些研究中很少有包含非裔美国人。纳入非裔美国人的研究提供的关联证据并不明确,且没有研究单独研究心力衰竭。我们使用来自社区动脉粥样硬化风险研究队列的数据,在非裔美国人中检查身体活动与 CVD 及其主要组成部分(中风、心力衰竭和 CHD)的发生之间的关系。

方法

参与者年龄在 45-64 岁(3707 名非裔美国人和 10018 名白种人,作为比较),在 1987 年通过问卷评估身体活动,并通过 2008 年的事件性 CVD(n=1039)进行随访。

结果

在调整了潜在混杂因素后,身体活动与 CVD、心力衰竭和 CHD 的发生在两个种族中呈负相关(趋势 P 值<0.0001),并且与非裔美国人的中风也呈负相关。每个更高身体活动类别的 CVD 风险比(95%置信区间)在种族间相似:非裔美国人分别为 1.0、0.65(0.56-0.75)和 0.59(0.49-0.71),白种人分别为 1.0、0.74(0.66-0.83)和 0.67(0.59-0.75)(交互 P 值=0.38)。

结论

我们的研究结果强化了定期身体活动对非裔美国人和白种人 CVD 风险降低均重要的建议,并支持一些身体活动总比没有好的观点。

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