Lee M J, Jarvik J G
Orthopedic Surgery and Sports Medicine, Neurological Surgery, University of Washington Medical Center, University of Washington, Seattle, WA 98195, USA.
Unfallchirurg. 2012 Dec;115(12):1066-9. doi: 10.1007/s00113-012-2307-8.
High-quality evidence has raised significant questions on the widespread use of vertebroplasty in the treatment of osteopenic vertebral insufficiency fractures. Further research is shifting the burden of proof on procedures such as balloon kyphoplasty and other interventions. New prospective clinical trials may need to consider including sham arms to enhance their relevance.
高质量证据对椎体成形术在骨质疏松性椎体压缩性骨折治疗中的广泛应用提出了重大质疑。进一步的研究正在将诸如球囊后凸成形术和其他干预措施的举证责任转移。新的前瞻性临床试验可能需要考虑纳入假手术组以提高其相关性。
