Bhivgade Sanjay, Melkote Shubha, Ghate Smita, Jerajani H R
Department of Dermatology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, India.
Indian J Dermatol. 2012 Nov;57(6):503. doi: 10.4103/0019-5154.103081.
Hereditary angioedema is a genetic disorder due to a deficiency or malfunction of C1 esterase inhibitor. We herein describe a case of 25-year-old male who presented with swelling over face since one day. There was history of similar episodes since two years with gradual subsidence of swelling without any treatment. Investigations revealed grossly reduced complement C4 and C1 esterase inhibitor level. Patient was diagnosed to have hereditary angioedema type 1 and started on stanozolol 2 mg three times a day with no recurrence in one year of follow-up. Hereditary angioedema resembles angioedema of an allergic reaction. However, the cause is different.
遗传性血管性水肿是一种由于C1酯酶抑制剂缺乏或功能异常引起的遗传性疾病。我们在此描述一例25岁男性患者，该患者自一天前开始出现面部肿胀。两年以来有类似发作史，肿胀在未经任何治疗的情况下逐渐消退。检查发现补体C4和C1酯酶抑制剂水平显著降低。患者被诊断为1型遗传性血管性水肿，并开始每天三次服用2毫克司坦唑醇，随访一年未复发。遗传性血管性水肿类似于过敏反应性血管性水肿。然而，其病因不同。
