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哮喘和慢性阻塞性肺疾病在原住民和非原住民人群中的流行情况:系统评价和流行病学研究的荟萃分析。

Prevalence of asthma and chronic obstructive pulmonary disease in Aboriginal and non-Aboriginal populations: a systematic review and meta-analysis of epidemiological studies.

机构信息

School of Public Health, Faculty of Medicine and Dentisttry, University of Alberta, Edmonton, Alberta.

出版信息

Can Respir J. 2012 Nov-Dec;19(6):355-60. doi: 10.1155/2012/825107.

DOI:10.1155/2012/825107
PMID:23248798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3603759/
Abstract

BACKGROUND

Asthma and chronic obstructive pulmonary disease (COPD) have considerable potential for inequities in diagnosis and treatment, thereby affecting vulnerable groups.

OBJECTIVE

To evaluate differences in asthma and COPD prevalence between adult Aboriginal and non-Aboriginal populations.

METHODS

MEDLINE, Embase, specialized databases and the grey literature up to October 2011 were searched to identify epidemiological studies comparing asthma and COPD prevalence between Aboriginal and non-Aboriginal adult populations. Prevalence ORs (PORs) and 95% CIs were calculated in a random-effects meta-analysis.

RESULTS

Of 132 studies, eight contained relevant data. Aboriginal populations included Native Americans, Canadian Aboriginals, Australian Aboriginals and New Zealand Maori. Overall, Aboriginals were more likely to report having asthma than non-Aboriginals (POR 1.41 [95% CI 1.23 to 1.60]), particularly among Canadian Aboriginals (POR 1.80 [95% CI 1.68 to 1.93]), Native Americans (POR 1.41 [95% CI 1.13 to 1.76]) and Maori (POR 1.64 [95% CI 1.40 to 1.91]). Australian Aboriginals were less likely to report asthma (POR 0.49 [95% CI 0.28 to 0.86]). Sex differences in asthma prevalence between Aboriginals and their non-Aboriginal counterparts were not identified. One study compared COPD prevalence between Native and non-Native Americans, with similar rates in both groups (POR 1.08 [95% CI 0.81 to 1.44]).

CONCLUSIONS

Differences in asthma prevalence between Aboriginal and non-Aboriginal populations exist in a variety of countries. Studies comparing COPD prevalence between Aboriginal and non-Aboriginal populations are scarce. Further investigation is needed to identify and account for factors associated with respiratory health inequalities among Aboriginal peoples.

摘要

背景

哮喘和慢性阻塞性肺疾病(COPD)在诊断和治疗方面存在相当大的不平等潜力,从而影响弱势群体。

目的

评估成人原住民和非原住民哮喘和 COPD 患病率的差异。

方法

检索 MEDLINE、Embase、专业数据库和截至 2011 年 10 月的灰色文献,以确定比较原住民和非原住民成人哮喘和 COPD 患病率的流行病学研究。采用随机效应荟萃分析计算患病率比值比(POR)和 95%置信区间。

结果

在 132 项研究中,有 8 项包含相关数据。原住民人群包括美洲原住民、加拿大原住民、澳大利亚原住民和新西兰毛利人。总体而言,原住民比非原住民更有可能报告患有哮喘(POR 1.41 [95%CI 1.23 至 1.60]),尤其是在加拿大原住民中(POR 1.80 [95%CI 1.68 至 1.93])、美洲原住民(POR 1.41 [95%CI 1.13 至 1.76])和毛利人(POR 1.64 [95%CI 1.40 至 1.91])。澳大利亚原住民报告哮喘的可能性较低(POR 0.49 [95%CI 0.28 至 0.86])。原住民和非原住民哮喘患病率的性别差异没有发现。一项研究比较了美国原住民和非原住民 COPD 的患病率,两组的患病率相似(POR 1.08 [95%CI 0.81 至 1.44])。

结论

在许多国家,原住民和非原住民哮喘患病率存在差异。比较原住民和非原住民 COPD 患病率的研究很少。需要进一步调查以确定和解释原住民呼吸健康不平等的相关因素。

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