Bowyer D J, Smillie I, Ganly I
Department of Otolaryngology/Head and Neck Surgery, Edinburgh Royal Infirmary, UK.
Department of Surgery, Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
J Laryngol Otol. 2013 Feb;127(2):175-80. doi: 10.1017/S0022215112002915. Epub 2012 Dec 18.
To review our experience with freehand core-needle biopsy in the assessment of unexplained head and neck masses.
A total of 770 patients with head and neck masses (referred over a 22-month period) were evaluated. A retrospective chart review was performed on 53 of those patients who underwent core-needle biopsy for an unexplained mass.
Correct sampling of the target tissue was achieved in all 53 patients (100 per cent) using a freehand core-needle biopsy technique. The diagnostic accuracy for providing adequate tissue samples for histopathological diagnosis was 96 per cent; the test sensitivity was 92 per cent. Four patients (7 per cent) required open surgical biopsy prior to commencing definitive treatment.
Out-patient freehand core-needle biopsy can be carried out safely on select patients with head and neck masses, and provides high quality histopathology specimens with high diagnostic utility.
回顾我们在运用徒手粗针活检评估不明原因的头颈部肿块方面的经验。
对770例头颈部肿块患者（在22个月期间转诊而来）进行了评估。对其中53例因不明原因肿块接受粗针活检的患者进行了回顾性病历审查。
使用徒手粗针活检技术，所有53例患者（100%）均成功获取了目标组织样本。为组织病理学诊断提供足够组织样本的诊断准确率为96%；检测敏感度为92%。4例患者（7%）在开始确定性治疗前需要进行开放性手术活检。
门诊徒手粗针活检可安全地应用于部分头颈部肿块患者，并能提供具有高诊断效用的高质量组织病理学标本。
