Pfeiffer Jens, Kayser Gian, Technau-Ihling Katja, Boedeker Carsten Christof, Ridder Gerd Jürgen
Department of Otorhinolaryngology-Head and Neck Surgery, Freiburg Medical School, Freiburg, Germany.
Head Neck. 2007 Nov;29(11):1033-40. doi: 10.1002/hed.20620.
Unclear cervicofacial masses are common presentations that often require tissue sampling to guide therapy. While open biopsy is invasive, fine-needle aspiration cytology includes a high rate of nondiagnostic samples.
A retrospective analysis on 181 core-needle biopsies in 88 patients was performed to determine the diagnostic efficacy of ultrasound-guided core-needle biopsies in the head and neck.
We experienced 100% success in obtaining high-quality histopathologic specimens. The target tissue was correctly sampled in 80 of 88 patients. In these patients the sensitivity, specificity, and accuracy rate of core-needle biopsies in differentiating benign from malignant cervicofacial lesions was 98.1%, 100%, and 98.8%, respectively.
Ultrasound-guided core-needle biopsies can be recommended as a safe and reliable technique in the diagnosis of cervicofacial masses with a high diagnostic yield. It obtains tissue samples of high quality and represents a sufficient alternative to open biopsy even in the diagnosis of lymphoma.
不明原因的面颈部肿块是常见的临床表现，通常需要进行组织取样以指导治疗。虽然开放性活检具有侵入性，但细针穿刺抽吸细胞学检查的非诊断性样本率较高。
对88例患者的181次粗针活检进行回顾性分析，以确定超声引导下粗针活检对头颈部疾病的诊断效能。
我们成功获取高质量组织病理标本的成功率为100%。88例患者中有80例正确采集到目标组织。在这些患者中，粗针活检鉴别面颈部良性与恶性病变的敏感性、特异性和准确率分别为98.1%、100%和98.8%。
超声引导下粗针活检可作为一种安全可靠的技术用于面颈部肿块的诊断，诊断率高。它能获取高质量的组织样本，即使在淋巴瘤的诊断中也足以替代开放性活检。
