山羊关节炎-脑炎病毒慢性感染中，关节炎的严重程度可通过对gp135的抗体反应来预测。
Severity of arthritis is predicted by antibody response to gp135 in chronic infection with caprine arthritis-encephalitis virus.
作者信息
Knowles D, Cheevers W, McGuire T, Stem T, Gorham J
机构信息
Animal Disease Research Unit, U.S. Department of Agriculture-Agricultural Research Service, Pullman, Washington 99164-7030.
出版信息
J Virol. 1990 May;64(5):2396-8. doi: 10.1128/JVI.64.5.2396-2398.1990.
Abstract
Antibody titers to caprine arthritis-encephalitis virus surface glycoprotein gp135 and core protein p28 in synovial fluid and serum from 35 goats infected for 3 years were compared with the histologic severity of arthritis in these animals. Anti-gp135 antibody titers in synovial fluid and serum directly reflect the severity of carpal arthritis in chronically infected goats.
摘要
对35只感染3年的山羊的滑液和血清中抗山羊关节炎-脑炎病毒表面糖蛋白gp135和核心蛋白p28的抗体滴度，与这些动物关节炎的组织学严重程度进行了比较。滑液和血清中的抗gp135抗体滴度直接反映了慢性感染山羊腕关节关节炎的严重程度。
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