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Quantitative determination of stanozolol and its metabolite in urine by gas chromatography/mass spectrometry.

作者信息

Choo H Y, Kwon O S, Park J

机构信息

Doping Control Center, Korea Advanced Institute of Science and Technology, Kangnam-ku, Seoul.

出版信息

J Anal Toxicol. 1990 Mar-Apr;14(2):109-12. doi: 10.1093/jat/14.2.109.

DOI:10.1093/jat/14.2.109
PMID:2325376
Abstract

The amount of stanozolol and 3'-hydroxystanozolol in urine was determined after oral administration of stanozolol. A gas chromatograph/mass selective detector equipped with a capillary column was used for these determinations. The GC/MS was operated in the SIM mode, and m/z 581, 669, and 315 were monitored for stanozolol, 3'-hydroxystanozolol, and calusterone (internal standard), respectively. The detection limit was approximately 1 ng/mL for both steroids. The maximum excretion rate of stanozolol was reached in 8 h and the maximum of 3'-hydroxystanozolol in 19 h. However, only 3% of the administered amount was recovered in urine.

摘要

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