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Clocking in on diabetic retinopathy.

作者信息

Kleinman Mark E, Ambati Jayakrishna

机构信息

Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, Kentucky, USA

出版信息

Diabetes. 2013 Jan;62(1):29-30. doi: 10.2337/db12-1151.

DOI:10.2337/db12-1151

PMID:23258909

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3526048/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ebb/3526048/4368e4cdba4b/29fig1.jpg

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本文引用的文献

Per2 mutation recapitulates the vascular phenotype of diabetes in the retina and bone marrow.

Diabetes. 2013 Jan;62(1):273-82. doi: 10.2337/db12-0172. Epub 2012 Nov 27.

Adrenergic nerves govern circadian leukocyte recruitment to tissues.

Immunity. 2012 Aug 24;37(2):290-301. doi: 10.1016/j.immuni.2012.05.021. Epub 2012 Aug 2.

Divergent roles of clock genes in retinal and suprachiasmatic nucleus circadian oscillators.

PLoS One. 2012;7(6):e38985. doi: 10.1371/journal.pone.0038985. Epub 2012 Jun 11.

Abrogation of MMP-9 gene protects against the development of retinopathy in diabetic mice by preventing mitochondrial damage.

Diabetes. 2011 Nov;60(11):3023-33. doi: 10.2337/db11-0816. Epub 2011 Sep 20.

Matrix metalloproteinase 2 and 9 dysfunction underlie vascular stiffness in circadian clock mutant mice.

Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2535-43. doi: 10.1161/ATVBAHA.110.214379. Epub 2010 Sep 9.

Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock.

J Exp Med. 2009 Dec 21;206(13):2897-906. doi: 10.1084/jem.20090889. Epub 2009 Nov 23.

Glucocorticoid regulation of the circadian clock modulates glucose homeostasis.

Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17582-7. doi: 10.1073/pnas.0909733106. Epub 2009 Oct 5.

Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription.

J Biol Chem. 2009 Sep 11;284(37):25149-59. doi: 10.1074/jbc.M109.040758. Epub 2009 Jul 15.

Increased vascular senescence and impaired endothelial progenitor cell function mediated by mutation of circadian gene Per2.

Circulation. 2008 Nov 18;118(21):2166-73. doi: 10.1161/CIRCULATIONAHA.108.790469. Epub 2008 Nov 3.

Circulating endothelial progenitor cells exhibit diurnal variation.

Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):e21-2. doi: 10.1161/ATVBAHA.107.160317.

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相似文献

Clocking in on diabetic retinopathy.

Diabetes. 2013 Jan;62(1):29-30. doi: 10.2337/db12-1151.

Per2 mutation recapitulates the vascular phenotype of diabetes in the retina and bone marrow.

Diabetes. 2013 Jan;62(1):273-82. doi: 10.2337/db12-0172. Epub 2012 Nov 27.

Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock.

J Exp Med. 2009 Dec 21;206(13):2897-906. doi: 10.1084/jem.20090889. Epub 2009 Nov 23.

Bone marrow-CNS connections: implications in the pathogenesis of diabetic retinopathy.

Prog Retin Eye Res. 2012 Sep;31(5):481-94. doi: 10.1016/j.preteyeres.2012.04.005. Epub 2012 May 15.

[Pathogenesis of diabetic retinopathy. I].

Klin Oczna. 1986 Aug;88(8):284-6.

Pathogenesis of diabetic retinopathy.

Diabetes. 1989 Oct;38(10):1203-6. doi: 10.2337/diab.38.10.1203.

[Relation of intraocular pressure, diabetes mellitus and diabetic retinopathy].

Rev Chir Oncol Radiol O R L Oftalmol Stomatol Ser Oftalmol. 1988 Jul-Sep;32(3):191-4.

Relationship between nerve function, retinopathy and duration of diabetes.

Eur J Pediatr. 1986 Dec;145(6):580-1. doi: 10.1007/BF02429076.

[Molecular pathogenesis of diabetic retinopathy].

Nihon Rinsho. 1997 Oct;55 Suppl:960-5.

Growth hormone and diabetic retinopathy.

Indian J Ophthalmol. 1983;31 Suppl:1049-52.

本文引用的文献

Per2 mutation recapitulates the vascular phenotype of diabetes in the retina and bone marrow.

Diabetes. 2013 Jan;62(1):273-82. doi: 10.2337/db12-0172. Epub 2012 Nov 27.

Adrenergic nerves govern circadian leukocyte recruitment to tissues.

Immunity. 2012 Aug 24;37(2):290-301. doi: 10.1016/j.immuni.2012.05.021. Epub 2012 Aug 2.

Divergent roles of clock genes in retinal and suprachiasmatic nucleus circadian oscillators.

PLoS One. 2012;7(6):e38985. doi: 10.1371/journal.pone.0038985. Epub 2012 Jun 11.

Abrogation of MMP-9 gene protects against the development of retinopathy in diabetic mice by preventing mitochondrial damage.

Diabetes. 2011 Nov;60(11):3023-33. doi: 10.2337/db11-0816. Epub 2011 Sep 20.

Matrix metalloproteinase 2 and 9 dysfunction underlie vascular stiffness in circadian clock mutant mice.

Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2535-43. doi: 10.1161/ATVBAHA.110.214379. Epub 2010 Sep 9.

Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock.

J Exp Med. 2009 Dec 21;206(13):2897-906. doi: 10.1084/jem.20090889. Epub 2009 Nov 23.

Glucocorticoid regulation of the circadian clock modulates glucose homeostasis.

Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17582-7. doi: 10.1073/pnas.0909733106. Epub 2009 Oct 5.

Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription.

J Biol Chem. 2009 Sep 11;284(37):25149-59. doi: 10.1074/jbc.M109.040758. Epub 2009 Jul 15.

Increased vascular senescence and impaired endothelial progenitor cell function mediated by mutation of circadian gene Per2.

Circulation. 2008 Nov 18;118(21):2166-73. doi: 10.1161/CIRCULATIONAHA.108.790469. Epub 2008 Nov 3.

Circulating endothelial progenitor cells exhibit diurnal variation.

Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):e21-2. doi: 10.1161/ATVBAHA.107.160317.